Postby roadrunner » Thu May 27, 2021 8:50 pm
I did two rounds of FOLFOX, 4 cycles each time. The first time ALT and AST were interesting indeed. I just did a quick look at the results, and saw values as high as AST 129 and ALT 299. They may have gone higher, but that range seems right for the higher end going by memory. My medical oncologist was never too concerned, but he did hold Oxi once and that seemed to help. I remember debating whether it was the Lovenox I was taking or the Oxi, but he was pretty strong about it being the Oxi, and the values did return to normal after chemo (though there is some literature on the body “acclimating” to Lovenox, so?) I did a lot of research at the time, and overall I don’t think it was a big deal. For what it’s worth, FOLFOX reduced my rectal tumor from close to 5 cm to a nCCR.
7/19: RC: Staged IIIA, T2N1M0
approx 4.25 cm, low/mid rectum, mod. well diff.; lung micronodule
8/19-10/19 4 rds.FOLFOX neoadjuvant, 3 w/Oxiplatin (reduced 70-75%)
neoadjuvant chemorad 11/19
4 rounds FOLFOX July-August 2020
ncCR 10/20; biopsies neg
TAE 11/20, tumor cells removed
Chest CT 3/30/21 growth in 2 nodules (3 and 5mm)
VATS 12/8/21 sub-pleural met 7mm.
SBRT nodule 1/22
6/20/22 TAE rectal polyp benign)
NED from 3/22 - 3/23
4 cycles FOLFIRI
LUL VATS lobectomy for radio resistant met 7/7/23