Importance of D levels

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MAPPING VITAMIN D DEFICIENCY,  
BREAST CANCER, AND COLORECTAL CANCER
SHARIF B. MOHR1
CEDRIC F. GARLAND1,2
EDWARD D. GORHAM1,2
WILLIAM B. GRANT3
ROBYN M. HIGHFILL1
FRANK C. GARLAND1,2
(1) Naval Health Research Center, San Diego CA 92186
(2) Department of Family and Preventive Medicine, School of Medicine, University of
California San Diego, La Jolla, CA
(3) Sunlight, Nutrition, and Health Research Center, San Francisco, CA
ABSTRACT
Breast and colorectal cancer incidence rates are highest in countries distant from the equator and lowest in near-equatorial countries. It is known that adequate levels of vitamin D, which require sunlight for synthesis in the skin, tend to be associated with lower age-adjusted incidence rates of these cancers. Residents of near-equatorial areas synthesize far more vitamin D than those living at high latitudes. To describe the associations of these cancers with ultraviolet B (UVB) rradiance, we obtained sunlight measurements from the National Aeronautics and Space Administration (NASA), and age-adjusted breast and colorectal cancer incidence rates for 175 countries from the International Agency for Research on Cancer Global Cancer Database (GLOBOCAN). We created Geographic Information Systems displays of the association between sunlight levels and disease rates using three-dimensional analysis. Countries that received the lowest solar irradiance had rates of breast and colorectal cancer that were several times greater than those of countries with the highest solar irradiance. Countries with intermediate irradiance had intermediate rates of colorectal and breast cancer incidence.

URL:
https://proceedings.esri.com/library/userconf/proc05/papers/pap1468.pdf