Great news. I had a PET Scan on Aprilt 14th and was NED, but my doctors ordered a new blood test that they said they will use to look for changes in the future. I've been getting CEA checks since the beginning and know about that one, but I didn't ask about what this new test was. The doctor did say it was a DNA cancer blood test. I though I'd read about a second blood test that is commonly done, but I couldn't find anything by searching DNA or blood tests. Does anyone know what I might be remembering?
Obviously I'll talk to my doctor once I get the results and find out then, but was just curious.
Remind me about DNA tests.
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JP66
- Posts: 64
- Joined: Sun Jan 21, 2024 8:42 am
- Facebook Username: joseph peck
- Location: Westchester, NY
Remind me about DNA tests.
Male born 3/66
10/23 TIIIbN+M1 - Stage IV common iliac lymph nodes metastatic
tumor 7.4 cm from AV, moderately differentiated
MSI-MSS; KRAS non-mutant
MD plan - Modified Neo-adjuvant Therapy
12/23 - 27 treatments rad+Xeloda
03/24 6 rounds FOLFIRINOX
5/24 TME/LAR + lymphadenectomy of common iliacs, temporary ileostomy
7/24 6 rounds FOLFOX
1/25 ileostomy reversal
4/25 PET Scan - NED
5/25 Signatera -neg
CEA (10/23-3/25) 1.8,1.3,1.6, 1.8, 1.6,2.1,2.7,2.4,1.4
10/23 TIIIbN+M1 - Stage IV common iliac lymph nodes metastatic
tumor 7.4 cm from AV, moderately differentiated
MSI-MSS; KRAS non-mutant
MD plan - Modified Neo-adjuvant Therapy
12/23 - 27 treatments rad+Xeloda
03/24 6 rounds FOLFIRINOX
5/24 TME/LAR + lymphadenectomy of common iliacs, temporary ileostomy
7/24 6 rounds FOLFOX
1/25 ileostomy reversal
4/25 PET Scan - NED
5/25 Signatera -neg
CEA (10/23-3/25) 1.8,1.3,1.6, 1.8, 1.6,2.1,2.7,2.4,1.4
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O Stoma Mia
- Posts: 1738
- Joined: Sat Jun 22, 2013 6:29 am
- Location: On vacation.
Re: Remind me about DNA tests.
Have you tried searching for keywords like:
Signatera
Guardant
ctDNA ?
Signatera
Guardant
ctDNA ?
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JP66
- Posts: 64
- Joined: Sun Jan 21, 2024 8:42 am
- Facebook Username: joseph peck
- Location: Westchester, NY
Re: Remind me about DNA tests.
O Stoma Mia wrote:Have you tried searching for keywords like:
Signatera
Guardant
ctDNA ?
Awesome. Thanks. I knew it was here somewhere. Just couldn't seem to find the right search terms, but that was, of course, it. Thanks again!
Male born 3/66
10/23 TIIIbN+M1 - Stage IV common iliac lymph nodes metastatic
tumor 7.4 cm from AV, moderately differentiated
MSI-MSS; KRAS non-mutant
MD plan - Modified Neo-adjuvant Therapy
12/23 - 27 treatments rad+Xeloda
03/24 6 rounds FOLFIRINOX
5/24 TME/LAR + lymphadenectomy of common iliacs, temporary ileostomy
7/24 6 rounds FOLFOX
1/25 ileostomy reversal
4/25 PET Scan - NED
5/25 Signatera -neg
CEA (10/23-3/25) 1.8,1.3,1.6, 1.8, 1.6,2.1,2.7,2.4,1.4
10/23 TIIIbN+M1 - Stage IV common iliac lymph nodes metastatic
tumor 7.4 cm from AV, moderately differentiated
MSI-MSS; KRAS non-mutant
MD plan - Modified Neo-adjuvant Therapy
12/23 - 27 treatments rad+Xeloda
03/24 6 rounds FOLFIRINOX
5/24 TME/LAR + lymphadenectomy of common iliacs, temporary ileostomy
7/24 6 rounds FOLFOX
1/25 ileostomy reversal
4/25 PET Scan - NED
5/25 Signatera -neg
CEA (10/23-3/25) 1.8,1.3,1.6, 1.8, 1.6,2.1,2.7,2.4,1.4
Re: Remind me about DNA tests.
It looks for tiny bits of cancer DNA floating in your blood so they can catch any changes even earlier than CEA. It’s not as routine as the CEA check yet, but more doctors are starting to use it for follow-up.
55 year at the time of diagnosis, male
Diagnosed with T1,T2 N0 M0 rectal cancer
Total neoadjuvant therapy or TNT (chemoradiation followed by systemic chemotherapy)
Negative since Feb. '17
No surgery
Watch&Wait approach
I don’t come much to the forum , so if this is not updated it means I remain negative!
Wish good luck to all!
Diagnosed with T1,T2 N0 M0 rectal cancer
Total neoadjuvant therapy or TNT (chemoradiation followed by systemic chemotherapy)
Negative since Feb. '17
No surgery
Watch&Wait approach
I don’t come much to the forum , so if this is not updated it means I remain negative!
Wish good luck to all!
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JP66
- Posts: 64
- Joined: Sun Jan 21, 2024 8:42 am
- Facebook Username: joseph peck
- Location: Westchester, NY
Re: Remind me about DNA tests.
mozart13 wrote:It looks for tiny bits of cancer DNA floating in your blood so they can catch any changes even earlier than CEA. It’s not as routine as the CEA check yet, but more doctors are starting to use it for follow-up.
Thanks!
Got the results back today. Normally blood work at the hospital shows up in minutes so I was expecting a couple days at most, but doctor today told me a Signatera test normally takes about 3 weeks. Anyways good news - it came back negative
I realize the war isn't over, but given my expectations when I was originally diagnosed I couldn't imagine a happier result at this point. LARS isn't fun and the steps to get here weren't fun, but it's WAY better than the alternative. Makes me a little more angry at Memorial Sloan Kettering though as they only offered me palliative chemo. Thank goodness I found a group of doctors willing to try the full monty Total Neoadjuvant Treatment.
Male born 3/66
10/23 TIIIbN+M1 - Stage IV common iliac lymph nodes metastatic
tumor 7.4 cm from AV, moderately differentiated
MSI-MSS; KRAS non-mutant
MD plan - Modified Neo-adjuvant Therapy
12/23 - 27 treatments rad+Xeloda
03/24 6 rounds FOLFIRINOX
5/24 TME/LAR + lymphadenectomy of common iliacs, temporary ileostomy
7/24 6 rounds FOLFOX
1/25 ileostomy reversal
4/25 PET Scan - NED
5/25 Signatera -neg
CEA (10/23-3/25) 1.8,1.3,1.6, 1.8, 1.6,2.1,2.7,2.4,1.4
10/23 TIIIbN+M1 - Stage IV common iliac lymph nodes metastatic
tumor 7.4 cm from AV, moderately differentiated
MSI-MSS; KRAS non-mutant
MD plan - Modified Neo-adjuvant Therapy
12/23 - 27 treatments rad+Xeloda
03/24 6 rounds FOLFIRINOX
5/24 TME/LAR + lymphadenectomy of common iliacs, temporary ileostomy
7/24 6 rounds FOLFOX
1/25 ileostomy reversal
4/25 PET Scan - NED
5/25 Signatera -neg
CEA (10/23-3/25) 1.8,1.3,1.6, 1.8, 1.6,2.1,2.7,2.4,1.4
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