Propranolol and Capecitabine Synergy

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utahgal7
Posts: 295
Joined: Fri Sep 11, 2020 12:04 pm

Propranolol and Capecitabine Synergy

Postby utahgal7 » Mon Apr 28, 2025 5:11 am

An article about combining the two aforementioned medications:

https://www.mdpi.com/2072-6694/17/9/1470
02/20 Rectal Cancer dx - 4 cm mass; located 9 cm from AV
CEA 2.7; 0.9; 1.4; 0.9; 0.9; 1.2; 1.0; 0.8; 1.1; 1.0; 1.1; 1.7; 1.8; 1.8
1.9; 2.4; 2.3; 2.8; 2.2, 2.8, 3.2; 3.0; 1.6; 2.0; 1.2; 1.4; 1.2; 1.0
04/20 ST Radiation; 04/20 LAR surgery w/ileostomy; ypT3N1bM0; MSS, KRAS G12A
05/20 CAPEOX; 08/20 Ileostomy reversal
12/20 CT scan; lung nodules (watch and wait);
11/22 lung nodule biopsy positive for RC met;
1/23 VATS right lower lobe wedge resection
FOLFIRI 10 cycles
4/24 left brain craniotomy (RC met)

Kaworu
Posts: 14
Joined: Tue Jun 21, 2016 12:37 am

Re: Propranolol and Capecitabine Synergy

Postby Kaworu » Sat May 03, 2025 12:35 pm

Interesting combo, especially given propranolol’s potential impact on stress pathways and tumor microenvironment. Curious to see how this holds up in clinical trials.

rp1954
Posts: 1875
Joined: Mon Jun 13, 2011 1:13 am

Re: Propranolol and Capecitabine Synergy

Postby rp1954 » Thu May 08, 2025 1:21 pm

Thanks, hope it extends more broadly for many more cancer types too.
watchful, active researcher and caregiver for stage IVb/c CC. surgeries 4/10 sigmoid etc & 5/11 para-aortic LN cluster; 8 yrs immuno-Chemo for mCRC; now no chemo
most of 2010 Life Extension recommendations and possibilities + more, some (much) higher, peaking ~2011-12, taper chemo to almost nothing mid 2018, IV C-->2021. Now supplements


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