CEA questions

Please feel free to read, share your thoughts, your stories and connect with others!
Jmy1975
Posts: 1
Joined: Thu Mar 28, 2024 8:14 pm

CEA questions

Postby Jmy1975 » Thu Mar 28, 2024 8:25 pm

I am new here, going through some difficult times.

My dad had stage2b rectal cancer. He is 80 and does not want want surgery. So in 2022 he went through oral chemo (pills) and radiation, and I gave him ivermectin.

By January 2023 the cancer was gone. His CEA was 1.11, down from 2.78. He had a small bump on his rectum.

In June of 2023 his MRI showed no cancer, however there was a 9mm bump which could be leftover tissue from the tumor or hemorrhoids. His CEA went up to 2.9 though, bigger than when he first had cancer.

This past January my dad got a CEA test and it was 10.6 . The bump on his rectum hasn't grown, according to him.

None of his two post treatment MRIs showed metastasis from the rectum. Yet his CEA is 10.6

Dad goes for a PET Scan on April 5 to look for tumors in his liver, etc.

Has anyone been in this situation? Can the high cea be a mistake? How could cancer metastasize in a place where there was no indication of metastasis?

Since he is 81 and chemo is very intolerable we don't want to do that, and we definitely don't want him to get a colostomy. Especially when his bump hasn't grown and he says he feels fine.

I hate cancer and wish this had never happened.

Thanks for sincere replies.

zephyr
Posts: 369
Joined: Thu Aug 18, 2016 7:31 am

Re: CEA questions

Postby zephyr » Fri Mar 29, 2024 11:27 am

It's probably not a mistake but it could be something unrelated. Cancer can metastasize anywhere in your body but there are also a number of benign conditions that can cause elevated CEA. For example, inflammation anywhere in your body can cause CEA to jump quite dramatically.
Nov-2009 Early stage CRC, routine colonoscopy
2010-2014 F/U colonoscopies, all clear
Jun-2016 CRC during F/U colonoscopy, surgery, Stage 4, KRAS, MSS
Aug-2016-May-2018 Folfox, 5FU, Folfiri & Avastin
Aug/Sep-2018 YAG laser surgeries (Germany), 11 nodules removed
Nov-2018 clean CT scan
Mar-2019 New lung nodules
Apr-2019 Dec-2020 Xeloda/Avastin, SBRT, cont. Xeloda/Avastin
Mar-2021 Forfiri/Avastin
Mar-2022 Ablation & Thoracotomy
Feb-2023 Folfiri & Avastin
Nov-2023 Xeloda & Avastin

roadrunner
Posts: 465
Joined: Sun Jan 12, 2020 8:46 pm

Re: CEA questions

Postby roadrunner » Fri Mar 29, 2024 1:20 pm

You haven’t provided enough information here. You say “the cancer was gone.” But how was that determined? It is not possible, by the way, to *know* a rectal tumor has been eliminated without resection and pathological analysis, though radiological evidence and the judgment of an expert surgeon can be reasonably accurate—recall that a microscopic amount of residual cancer cells can cause a recurrence. You appear to note a subsequent “9mm bump” at or near the tumor site. That suggests local recurrence, but does not confirm it. The rising CEA could be caused by such a recurrence, as well. Distant metastasis, also, cannot always be detected on scans. So the CEA could be due to that. CEAs over 10 usually indicate malignancy, but not always. From what you’ve said—and it’s very limited, so this isn’t worth much—I’d focus on that “9mm bump” first, then worry about metastasis.
7/19: RC: Staged IIIA, T2N1M0
approx 4.25 cm, low/mid rectum, mod. well diff.; lung micronodule
8/19-10/19 4 rds.FOLFOX neoadjuvant, 3 w/Oxiplatin (reduced 70-75%)
neoadjuvant chemorad 11/19
4 rounds FOLFOX July-August 2020
ncCR 10/20; biopsies neg
TAE 11/20, tumor cells removed
Chest CT 3/30/21 growth in 2 nodules (3 and 5mm)
VATS 12/8/21 sub-pleural met 7mm.
SBRT nodule 1/22
6/20/22 TAE rectal polyp benign)
NED from 3/22 - 3/23
4 cycles FOLFIRI
LUL VATS lobectomy for radio resistant met 7/7/23

User avatar
Green Tea
Posts: 461
Joined: Mon Oct 24, 2016 10:48 am

Re: CEA questions

Postby Green Tea » Fri Mar 29, 2024 10:13 pm

roadrunner wrote:You haven’t provided enough information here.

Jmy1975
Welcome to ColonTalk. I'm sorry to hear about your father's situation and the rise in CEA. There are some members here who might be able to provide some feedback, but as roadrunner has already said, more information is needed for us to understand the situation.

One way to provide us with information is for you to prepare a signature here containing the important elements of your father's diagnosis and treatment. Here is a link for doing that:

https://coloncancersupport.colonclub.com/viewtopic.php?f=1&t=52681&p=421597#p421597

User avatar
Green Tea
Posts: 461
Joined: Mon Oct 24, 2016 10:48 am

CEA (Carcinoembryonic Antigen)

Postby Green Tea » Sat Mar 30, 2024 1:26 am

zephyr wrote:It's probably not a mistake but it could be something unrelated. Cancer can metastasize anywhere in your body but there are also a number of benign conditions that can cause elevated CEA. For example, inflammation anywhere in your body can cause CEA to jump quite dramatically.

CEA (Carcinoembryonic Antigen)
https://coloncancersupport.colonclub.com/viewtopic.php?f=1&t=65967&p=510814#p510814


Return to “Colon Talk - Colon cancer (colorectal cancer) support forum”



Who is online

Users browsing this forum: Google [Bot] and 59 guests