fusobacterium nucleatum

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beach sunrise
Posts: 1023
Joined: Thu Mar 05, 2020 7:14 pm

fusobacterium nucleatum

Postby beach sunrise » Mon Jan 15, 2024 3:48 pm

Digging deeper into markers that are out of whack and came across f nucleatum. Hmmm
I was checked several years ago for gut bacteria but oddly this one was not on the check list. I will have to have this one checked.
I found aspirin, berberine, EGCG, theoflavin and AgNP helps kill it and a few anti-biotics..
[ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832957/]
8/19 RC CEA 82.6 T3N0M0
5FU/rad 6 wk
IVC 75g 1 1/2 wks before surgery. Continue 2x a week
Surg 1/20 -margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
pre cea 24 post 5.9
FOLFOX
7 rds 6-10 CEA 11.4 No more
CEA
7/20 11.1 8.8
8/20 7.8
9/20 8.8, 9, 8.6
10/20 8.1
11/20 8s
12/20 8s-9s
ADAPT++++ chrono
CEA
10/23/22 26.x
12/23/22 22.x
2023
1/5 17.1
1/20 15.9
3/30 14.9
6/12 13.3
8/1 2.1
Nodule RML SUV 1.3 5mm
Rolles 3 of 4 lung nodules cancer
KRAS
Chem-sens test failed Not enough ca cells to test

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Peregrine
Posts: 255
Joined: Tue Mar 01, 2022 1:18 am

Re: fusobacterium nucleatum

Postby Peregrine » Tue Jan 16, 2024 8:01 am

Just some thoughts...

1. You might get responses from people if they recognize your tumor mutations. So, if you update your signature with KRAS Q61H, POLD, and TP53, it might help elicit some feedback.
.
2. It might help to read up more on biomarkers and gut microbiome.

https://fightcolorectalcancer.org/facing-colorectal-cancer/colorectal-cancer-biomarkers/

https://fightcolorectalcancer.org/blog/the-gut-microbiome-2

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beach sunrise
Posts: 1023
Joined: Thu Mar 05, 2020 7:14 pm

Re: fusobacterium nucleatum

Postby beach sunrise » Wed Jan 17, 2024 11:21 am

Thanks, Peregrine! You always have great info to share.
8/19 RC CEA 82.6 T3N0M0
5FU/rad 6 wk
IVC 75g 1 1/2 wks before surgery. Continue 2x a week
Surg 1/20 -margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
pre cea 24 post 5.9
FOLFOX
7 rds 6-10 CEA 11.4 No more
CEA
7/20 11.1 8.8
8/20 7.8
9/20 8.8, 9, 8.6
10/20 8.1
11/20 8s
12/20 8s-9s
ADAPT++++ chrono
CEA
10/23/22 26.x
12/23/22 22.x
2023
1/5 17.1
1/20 15.9
3/30 14.9
6/12 13.3
8/1 2.1
Nodule RML SUV 1.3 5mm
Rolles 3 of 4 lung nodules cancer
KRAS
Chem-sens test failed Not enough ca cells to test

skimom
Posts: 69
Joined: Fri Mar 17, 2023 12:24 pm
Location: Oregon USA

Re: fusobacterium nucleatum

Postby skimom » Wed Jan 17, 2024 9:49 pm

Hi beach sunrise.. thinking of you & praying your scans went well yesterday :)
47yo F at DX
DX 12/11/22 Stage IV (liver & lung mets) KRAS PIK3CA
12/15/22 Primary tumor removed from Transverse Colon (4.3x4.0x0.6cm G2 3/15 lymph nodes. Clear margins)
01/06/23 started Folfox (10 cycles)
Initial CEA 5608
CEA after 4 rounds 1319
CEA after 6 rounds 427
CEA after 9 rounds 95
HAI pump installed 06/20/23
Start FOLFIRI and FUDR 07/05/23
CEA down to 37
31
21
18
9/2023 Switch back to FOLFOX due to new lung nodules
11/23 FOLFOX fail CEA up to 62


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