postbiotic

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beach sunrise
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Joined: Thu Mar 05, 2020 7:14 pm

postbiotic

Postby beach sunrise » Sat Oct 28, 2023 9:09 am

Giménez-Bastida, J. A., Ávila-Gálvez, M. Á., Espín, J. C., & González-Sarrías, A. (2020). The gut microbiota metabolite urolithin A, but not other relevant urolithins, induces p53-dependent cellular senescence in human colon cancer cells. Food and Chemical Toxicology, 111260. doi:10.1016/j.fct.2020.111260 10.1016/j.fct.2020.111260

https://pubmed.ncbi.nlm.nih.gov/29932926/


Ya, down the rabbit hole today about p53 amd macrophages.
8/19 RC CEA 82.6 T3N0M0
5FU/rad 6 wk
IVC 75g 1 1/2 wks before surgery. Continue 2x a week
Surg 1/20 -margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
pre cea 24 post 5.9
FOLFOX
7 rds 6-10 CEA 11.4 No more
CEA
7/20 11.1 8.8
8/20 7.8
9/20 8.8, 9, 8.6
10/20 8.1
11/20 8s
12/20 8s-9s
ADAPT++++ chrono
CEA
10/23/22 26.x
12/23/22 22.x
2023
1/5 17.1
1/20 15.9
3/30 14.9
6/12 13.3
8/1 2.1
Nodule RML SUV 1.3 5mm
Rolles 3 of 4 lung nodules cancer
KRAS
Chem-sens test failed Not enough ca cells to test

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