Rock_Robster wrote:Hi all, just to close this one out - my 6 week scans unfortunately showed the trial drug wasn’t working. Increase in size and number of liver metastases, and small increase in size of lung lesions. Won’t be continuing.
Of course that sucks, but on with the show.
I have two questions.
What was the physical cost of the Atrium trial in terms of side effects and blood panels?
What % of your work are you functioning at or willing to give up to work harder on yourself?
Thanks RP. Good questions as always.
Side effects minimal, a bit more cumulative fatigue. My liver enzymes are beginning to creep up again, but onc believes that’s more related to hep disease progression than the trial drug (but who knows).
I’m currently at about 80-90% capacity. I’m working full-time, I lead a team of 6 in a multinational. But I can work flexibly / from home, which is great. Ongoing fatigue and diarrhea are my main challenges.
I’m prepared to give up almost everything if it puts a reasonable outcome on the table (doesn’t have to be ‘cure’, but durable stable would at least be good). I don’t have to work - I have good life insurance through my employer and could take medical retirement now and get a payout. That said, I enjoy working and it makes sense to do while I can. My challenge is the main ‘sacrificial’ treatments being shown to me are conventional chemo - ie back on XELIRI, or Lonsurf+Avastin. Neither of those are interesting to me. They’re talking about SIRT/Y90 to buy me some liver time, which I’m fine with. But I really need a good trial, something properly novel but not one of these Hail Mary’s that are on really shaky data.
Will keep working the problem as always.