Update on bot/bal trial: the phase 2 trial closed before my husband could get in, and phase 3 trial will be for first-line patients only. But! His oncologist applied to the company for compassionate use access to the drugs and we were approved, so he will be starting in 3 weeks, after Folfiri washout period.
I’m feeling hopeful because right now he has only lung nodules, with maybe some new lymph nodes, and lung-only metastasis seems to have the been chance of success on this trial.
NIH also contacted us about TIL, because his latest scans now show a lung nodules large enough to harvest. We are setting an appt there for after his first scans on bot/bal, and will cancel if the trial drugs are working.
husband (age 41 at dx):
8/20 CRC Stage 4. Mets to lungs, liver, distant lymph nodes
MSS, KRAS wild
CEA 713 at dx
Folfox (12 rounds)
Liver, colon and node resection 4/21
New lung mets, Vectibix monotherapy started 6/21
Stop Vectibix lungs stable about 6 months; all other areas stable
Start Folfiri + avastin 1/22
Stop Folfiri (lungs stable 6 mos); start Vectibix 7/22
Stop Vectibix 12/22 (lungs stable 5 mos this time)
SBRT on lung Mets scheduled for 1/22, will restart Folfiri