Postby roadrunner » Sat Dec 10, 2022 3:00 pm
Welcome. This forum is a really great resource. The posters bring lots of experience and a diversity of perspectives and approaches. Reading about similar circumstances, treatments, and experiences to yours can be very helpful in informing your own decisions and just in staying sane. Like Peregrine’s, my path is pretty different from yours, so at this point, I don’t have a ton of observations about what you’ve written.
I would venture to throw out the following, very high level comments: From what I know, MSS status alone is not a bad prognostic factor, though MSI does open up treatment options (primarily immunotherapy, which doesn’t at present work well for most MSS patients; that is very possibly the next frontier in CRC treatment). Poor differentiation is an issue,I believe, so it may be worth it to research there. Overall, as I suspect you know, the trick is to avoid metastasis. You didn’t say, but I assume you’ve been scanned and came up clear. That’s a good start. It sounds like your lymph nodes came up clear as well, which is also really good.
Finally, you’ll see widely divergent views on alternative therapies, supplementation, diet, etc. You seem open to it,
And there are a number of folks on here who are very committed to it, and post often, with lots of information. My approach has been more focused on exercise (run 3 mi/day (getting to 3+), walk when I can’t run, and diet (eliminated alcohol, reduced sugar, tons of blueberries, cranberries, mushrooms, tea and coffee, veggies, very little red meat). I’m not intrinsically opposed to supplementation (e.g., there’s decent evidence supporting infusional vitamin C for various reasons), but my only caution is to always remember that your immune system is the hero here, so I’d research and watch carefully to make sure any alternative approaches do not adversely impact you there. My 2 cents.
7/19: RC: Staged IIIA, T2N1M0
approx 4.25 cm, low/mid rectum, mod. well diff.; lung micronodule
8/19-10/19 4 rds.FOLFOX neoadjuvant, 3 w/Oxiplatin (reduced 70-75%)
neoadjuvant chemorad 11/19
4 rounds FOLFOX July-August 2020
ncCR 10/20; biopsies neg
TAE 11/20, tumor cells removed
Chest CT 3/30/21 growth in 2 nodules (3 and 5mm)
VATS 12/8/21 sub-pleural met 7mm.
SBRT nodule 1/22
CT 3/22: Clear
Chest CT 5/19/22 Clear
6/20/22 TAE rectal polyp benign
CT/MRI 9/11 Clear
11/9/22: Rectal exam/scope Clear (2 yrs.)