Pain with unknown source

[Nor Cal]

HI all -

Since June, 2022 I have been experiencing (~1-2 times per month) a strange pain which begins in the middle of my back right at the spine. Over the course of an hour or so it spreads around to my stomach, so that my whole lower torso is in pain. And the pain level is completely debilitating (a 10 on a 1-10 scale). It always starts while I'm sleeping, and typically lasts 3-6 hours. I've been to the ER three times with this. I've also had multiple Ct scans (chest, abdomen, pelvis), and MRIs (focused on my liver, but it captures quite a bit more). And the results are always the same - nothing. The only pain med that seems to have any impact is the dilaudid they give me in the ER.

My chemo during all of this is Xeliri (Xeloda and Irinotecan).

Does anyone have experience with something like this? We've tried to make connections to diet and day-of-cycle, but no luck. It's random as far as we can tell. Any insight would be much appreciated.

[MadMed]

I have pain in my lower back. It’s apparently attributable to radiation damage,the CT shows nothing, but the MRI does:

Suspected post-radiation changes of the sacrum.

It usually flares up when I’m laying on my back for a while.

[Nor Cal]

Thanks MadMed. I'll check with my liver guy to see if he thinks this is post-treatment changes from the radioembolization.