Memorial sloan watch and wait predictor

Please feel free to read, share your thoughts, your stories and connect with others!
MadMed
Posts: 186
Joined: Sun May 02, 2021 5:52 pm
Location: Massachusetts

Memorial sloan watch and wait predictor

Postby MadMed » Tue Oct 18, 2022 11:08 am

MSK has just published a tool to help with watch-and-wait or not. The actual study is here:
https://pubmed.ncbi.nlm.nih.gov/36173634/

It's not huge numbers, so the prediction is going to be adjusted over time like their other tools. But this should start giving the tools to decide whether to W&W or go for surgery.
Also, there's a big caveat, this is after TNT with a robust surveillance program. Otherwise the numbers don't hold.

The calculator link: https://www.mskcc.org/nomograms/colorec ... rgery_wait it gives DFS odds.
52M DX: RC lower rectum, guessing now 2cm from AV 4/27/2021
T3N0M0 adenocarcinoma with signet ring cell features
Tumor size 30mm
Tumor grade: G3
Baseline CEA 1.0
MSI status: MSS pMMR
Started Folfox 5/12/2021
Switched to FOLFIRINOX from session 2. 8 rounds total.
CT+MRI tumor contained shrunk 80%, no spread to other organs.
CRT started xeloda + 28 days Radiation 9/27-11/04
NED as of 4/06 CT/MRI/sigmoidoscopy
On W&W 04/06/2022

User avatar
CRguy
Posts: 10405
Joined: Sun Feb 10, 2008 6:00 pm

Re: Memorial sloan watch and wait predictor

Postby CRguy » Mon Nov 21, 2022 11:44 pm

Thanks for this head's up.

I believe ALL the info and brain work we can throw at CRC ( and all cancers for that matter )
will only help to move our treatment success rates forward, diagnostics forward and preventives forward.

Just another small part of the puzzle ... BUTT
we have to keep looking at it ALL !!!

Cheers
CRguy
Caregiver x 4
Stage IV A rectal cancer/lung met
15 Year survivor
my life is an ongoing totally randomized UNcontrolled experiment with N=1 !
Review of my Journey so far


Return to “Colon Talk - Colon cancer (colorectal cancer) support forum”



Who is online

Users browsing this forum: No registered users and 6 guests