SBR for metasticized colon cancer in lung

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ASTEPHENS33
Posts: 352
Joined: Wed Dec 14, 2005 10:04 pm
Location: Seattle, Washington
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SBR for metasticized colon cancer in lung

Postby ASTEPHENS33 » Tue Aug 23, 2022 11:29 pm

Anyone hae experience with this? Side effects? Any tips on how to handle it? Colon cancer had gone into the lungs and after 3 years has started to grow. The plan is to do SBR radiation and then chemo. Thanks.

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Jacques
Posts: 607
Joined: Sun Dec 28, 2014 10:38 am
Location: Occitanie

Re: SBR for metasticized colon cancer in lung

Postby Jacques » Tue Aug 23, 2022 11:55 pm

ASTEPHENS33 wrote:Anyone hae experience with this? Side effects? Any tips on how to handle it? Colon cancer had gone into the lungs and after 3 years has started to grow. The plan is to do SBR radiation and then chemo. Thanks.

Here are a few recent posts on that topic:

SABR / SBRT for lung nodules

roadrunner
Posts: 286
Joined: Sun Jan 12, 2020 8:46 pm

Re: SBR for metasticized colon cancer in lung

Postby roadrunner » Wed Aug 24, 2022 10:22 am

ASTEPHENS33:

There are a lot of people on this board who have had SBRT for pulmonary metastases, and quite a few threads can be found easily. However, each situation is unique, and there are several potential alternatives.

If you’re looking for general info, threads like those forwarded by Jacques may be very helpful. If you want the benefit of members’ nuanced reaction to your situation, it is important to provide information about your specific circumstances and questions, and optimal to provide a relatively detailed signature. Good luck!
7/19: Rectal cancer: Staged IIIA, T2N1M0
approx 4.25 cm, low/mid rectum, mod. well diff.; lung micronodule
8/22 -10/14 4 rounds FOLFOX neoadjuvant, 3 w/Oxiplatin (side effects/reduced 70-75%)
neoadjuvant chemorad 11/19
4 rounds FOLFOX July-August 2020
ncCR 10/20; biopsies neg
TAE 11/20, tumor cells removed
Chest CT 3/30/21 small growth in 2 nodules (3 and 5mm)
VATS 12/8/21 sub-pleural met 7mm.
SBRT nodule 1/22
CT 3/22: Clear
Thoracic CT 5/19/22 Clear
6/20/22 TAE rectal polyp benign
CT/MRI 9/11 Clear

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Jacques
Posts: 607
Joined: Sun Dec 28, 2014 10:38 am
Location: Occitanie

Re: SBR for metasticized colon cancer in lung

Postby Jacques » Thu Aug 25, 2022 12:07 am

ASTEPHENS33 -

You don't have a signature right now, however it appears from your previous posts that you are a Stage IIIA female colon cancer patient NED since completion of your Xeloda adjuvant therapy back in February 2006, but that you are now inquiring about SBRT for an 8mm lung met on behalf of a friend of yours who has metastatic cancer. Is that correct?

ASTEPHENS33 wrote:8mm tumor on lung. Do they normally do a biopsy or just monitor?

ASTEPHENS33 wrote:It has grown. Talking to the doctor on Wednesday about next steps. Hope you’re ok, too. I’m posting for a friends actually

Can you provide more information about the actual situation, and who it is who has the growing lung met? Is it you or someone else?

Rock_Robster
Posts: 702
Joined: Thu Oct 25, 2018 5:27 am
Location: Brisbane, Australia

Re: SBR for metasticized colon cancer in lung

Postby Rock_Robster » Thu Aug 25, 2022 5:14 am

I had SABR recently for some liver mets, and I understand lung SABR is generally considered ‘easier’ than this as you have less GI upset to deal with (eg nausea vomiting). The hardest part is laying extremely still in a quite awkward position for a fairly long period (30+ mins) for each treatment, and doing the breathing exercises to keep the organs in the right place. Also the fatigue is REAL - I had never felt anything quite like that before (I would sweat from making myself a coffee). The good thing is you do recover pretty fast; within a couple of weeks a felt a LOT better, and within about 6 weeks I’d say I was basically over it. And the other good news is it’s usually very effective - everything they hit was dead on the next scan.
40M Australia
2018 RC, 12cm high
G2 EMVI LVI. 4 liver mets
pT3N1aM1a Stage IVa MSS NRAS G13R
CEA: Nov-18: 14 then <2. Jun-22: 5. Sep-22: 10
11/18 FOLFOX
3/19 Liver resection
5/19 Pelvic IMRT
7/19 ULAR & ileo
8/19 Liver met
8/19 FOLFOX, FOLFOXIRI, FOLFIRI
12/19 Liver resection
NED 2 years
11/21 Liver met & node, 2 tiny lung things
12/21 PVE
3/22 Nodes & 3 liver mets. Lymphadenectomy
4/22 Liver SBRT
6/22 Liver clear.
10/22 Small liver spot. Some PALNs. Planning PALN SBRT.

roadrunner
Posts: 286
Joined: Sun Jan 12, 2020 8:46 pm

Re: SBR for metasticized colon cancer in lung

Postby roadrunner » Thu Aug 25, 2022 10:15 am

Rob: Just for the record, SBRT to the lungs is indeed quite a lot easier than what you describe for the liver. At least in my experience. While YMMV, there were virtually zero side effects. I believe there’s a short hit to WBCs (because they cycle through the beams), but then the immune system is often moderately boosted for at least six months (mine seems to have been). There was no fatigue, nausea, or pain. Perhaps there are issues if the targets are large, but others would have to chime in on that. I do agree about the breath holds being the most interesting bit. They let you pick how long to hold within a range, and I pushed it to get fewer holds, but you can find a sweet spot. No biggie once you get the hang of the machine. I will say that I initially misread your reference to “30+ minutes” as about the breath holds, and my first response was “Dang, they really are tougher in Australia.” :shock:
7/19: Rectal cancer: Staged IIIA, T2N1M0
approx 4.25 cm, low/mid rectum, mod. well diff.; lung micronodule
8/22 -10/14 4 rounds FOLFOX neoadjuvant, 3 w/Oxiplatin (side effects/reduced 70-75%)
neoadjuvant chemorad 11/19
4 rounds FOLFOX July-August 2020
ncCR 10/20; biopsies neg
TAE 11/20, tumor cells removed
Chest CT 3/30/21 small growth in 2 nodules (3 and 5mm)
VATS 12/8/21 sub-pleural met 7mm.
SBRT nodule 1/22
CT 3/22: Clear
Thoracic CT 5/19/22 Clear
6/20/22 TAE rectal polyp benign
CT/MRI 9/11 Clear

Markdale
Posts: 41
Joined: Wed Dec 02, 2020 4:45 pm

Re: SBR for metasticized colon cancer in lung

Postby Markdale » Thu Aug 25, 2022 7:57 pm

I had sabr to to 2 spots in the right lung. Did not notice any effect, the positioning and the staying still is the hardest. The radiation onc said there could be some rib pain because of the location of one of the spots but I felt nothing.
09/20:Diagnosed after colonoscopy for bleeding.
MRI and ct scan confirmed tumor at rectosigmoid junction aswell as lung nodules in RLL (1X1.2cm) and RUL (3X.5cm)
10/20: low anterior resection tumour t3n2m1 4/24 lymph nodes. No ileostomy.
11/20: pet scan showed low to moderate uptake of glucose.
11/20: folfoxiri - 10/6/21. 12 rounds in total
12/20: ct lung biopsy of lung nodule to confirm metastasis. Biopsy unsuccessful
1/1/21 thoracotomy (unsuccessful)
2/2022 sabr to 2 lung nodules


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