Hi all, I was dx stage II high risk and underwent left hemicolon surgery in july 2020 followed by 3 months CAPOX.
I had my first Signatera test done in june 2022, almost two years after surgery.
The results are negative (as is no trace of ctDNA could be detected). Obviously this makes me very happy.
Now we all know Signatera is not very sensitive (I am reading 50-60% sensitivity on a single measurement). We also know that Signatera is not very good at picking lung mets (which are unlikely to be the first metastasic site for colon cancer anyway)
Do you think that the fact that I had this test done almost two years after surgery may improve it? I mean at least theoretically, by now if viable cancer cells had been left in the body they should have already multiplied enough to be detectable, shouldn´t they?
I will obvioulsy continue my surveillance and repeate Signatera over the next few months but I wanted your opinion.
Thank you and best regards
Javi