So…………..some new curve balls.
About 50% of the time the harvested TILs do not react to, or the reaction to the tumor cells in the lab is too weak, and this means the procedure would be ineffective, and hence, not pursued. We will know in two weeks.
Additionally, they will not perform the infusion/procedure unless the cancer is progressing.
Serious curveball as I have started opdivo/yervoy after sbrt a few weeks ago.
I like to list all potential outcomes to determine what my best course of action would be.
1) TILs don’t respond so my only recourse is to pursue the opdivo/yervoy every three weeks for up to two years unless there is progression or side effects become unbearable.
2) TILs respond but lesions are shrunk by the opdivo/yervoy in which caseI would pursue opdivo/yervoy until progression.
3) TILs respond, but lesions do not respond to opdivo/yervoy would mean TIL infusion after a one month washout.
4) TILs respond, but SBRT/opdivo/yervoy achieve regression in all lung lesions. TILs would be held in reserve indefinitely.
I have no idea what to root for now.
My head is spinning as I am tossed back into limbo and facing the prospect of immunotherapy until my disease gets worse
, or that treatments don’t work at all.
Will be going back and adding my previous protocols sans the cbd.
Might as well try and kill as much as I can while doing the immunotherapy.
Part of me wants to just say “ Fuck it, I’m done.” Three years is enough already.
The loneliness is almost unbearable.