Postby roadrunner » Tue Oct 24, 2023 1:30 pm
I understand. And this is probably obvious, but if you’re thinking about ablation as a possible “Plan B,” def keep a close eye on size. RFA limit is around 3 cm I believe. I’m less sure of cryoablation, but perhaps that’s a good benchmark there too? Of course, location matters. SBRT is also an option, but it looks like you already had one escape that treatment (as have I), so perhaps not as attractive. Finally, as previously mentioned, surgery could become available down the road. Again, using the TILs seems an optimal plan at present, but I would keep an eye on size and location as that goes forward. If it doesn’t eradicate all disease, you will need to know when to open any available parachutes.
7/19: RC: Staged IIIA, T2N1M0
approx 4.25 cm, low/mid rectum, mod. well diff.; lung micronodule
8/19-10/19 4 rds.FOLFOX neoadjuvant, 3 w/Oxiplatin (reduced 70-75%)
neoadjuvant chemorad 11/19
4 rounds FOLFOX July-August 2020
ncCR 10/20; biopsies neg
TAE 11/20, tumor cells removed
Chest CT 3/30/21 growth in 2 nodules (3 and 5mm)
VATS 12/8/21 sub-pleural met 7mm.
SBRT nodule 1/22
6/20/22 TAE rectal polyp benign)
NED from 3/22 - 3/23
4 cycles FOLFIRI
LUL VATS lobectomy for radio resistant met 7/7/23