I ended up having 8, though Oxi was pulled or limited for two. I had a lot of conversations with my team that suggested 6 was enough. I think I also saw studies indicating that 6 wasn’t different from 8 on many important measures, though I have only a vague memory there at this point (might be worth a look). I would add, though, that unless you have serious neuropathy issues or dangerous complications, my two cents is that you will feel better in the future if you finish the 8. I got a very big benefit from it, but I think most of the measurable benefit occurred in the first 4. It’s hard to say about “success.” That’s the reason for a conservative approach.
7/19: Rectal cancer: Initially staged as IIIA, T2N1M0
Initially approx 4.25 cm, low/mid rectum, mod. well diff. adenocarcinoma
8/22 -10/14 4 rounds FOLFOX neoadjuvant, 3 w/Oxiplatin (lots of side effects/reduced size est. 70-75%)
neoadjuvant chemorad 11/19
4 rounds of FOLFOX July-August 2020
ncCR found 10/20; multiple biopsies negative
TAE 11/20, small amount of tumor removed, lung nodules orig id’d 6/20 stable Nov 2020
Chest CT 3/30/21 small growth in 2 nodules (3 and 5mm)
Stable in 6/28 scan.