Prenuvo

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saltygirl
Posts: 169
Joined: Sun Feb 07, 2021 4:46 pm
Facebook Username: Salty.girl

Prenuvo

Postby saltygirl » Fri Aug 27, 2021 7:30 pm

https://www.prenuvo.com/

Anybody is using it instead of CT scans?
Stage 4, distant lymph nodes May 2020, braf/kras mutations
11 folfoxiri
Intense radiation 1 week on distant lymph nodes
Surgery, hysterectomy, colon resection, distant lymph nodes resection
Complete pathological response to chemo.
NED 2021
NED 2022
NED 2023

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beach sunrise
Posts: 1041
Joined: Thu Mar 05, 2020 7:14 pm

Re: Prenuvo

Postby beach sunrise » Fri Aug 27, 2021 11:22 pm

Heard about it and asked for more info. Email I got said it screens for over 500 cancers and diseases. Can detect earlier than other scanning techniques.
8/19 RC CEA 82.6 T3N0M0
5FU/rad 6 wk
IVC 75g 1 1/2 wks before surgery. Continue 2x a week
Surg 1/20 -margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
pre cea 24 post 5.9
FOLFOX
7 rds 6-10 CEA 11.4 No more
CEA
7/20 11.1 8.8
8/20 7.8
9/20 8.8, 9, 8.6
10/20 8.1
11/20 8s
12/20 8s-9s
ADAPT++++ chrono
CEA
10/23/22 26.x
12/23/22 22.x
2023
1/5 17.1
1/20 15.9
3/30 14.9
6/12 13.3
8/1 2.1
Nodule RML SUV 1.3 5mm
Rolles 3 of 4 lung nodules cancer
KRAS
Chem-sens test failed Not enough ca cells to test

Rock_Robster
Posts: 1028
Joined: Thu Oct 25, 2018 5:27 am
Location: Brisbane, Australia

Re: Prenuvo

Postby Rock_Robster » Sun Aug 29, 2021 4:21 am

On very short review it just seems to be a full-body MRI, which has the benefit of negligible radiation dose, but isn’t the best medium for detecting some cancers and metastasis (eg lung, lymph nodes). I’m also guessing it’s not targeted enough in dosimetry and contrast etc. for some specific body parts which are most concerning for CRC metastases (eg liver). Without claiming to be an expert by any stretch, I’d be suggesting that the best surveillance protocol is one developed by your oncologist/surgeon using evidence-based guidelines, not one marketed by a private company. My surveillance routine has involved a combination of CT and PET-CT, interspersed with dedicated liver MRIs, to get the best overall coverage and sensitivity.

Might be ok if you didn’t have cancer and just wanted some peace-of-mind, but for a post-diagnosis surveillance regime where getting the right early detection can truly mean life-or-death, I wouldn’t personally be taking any chances!
41M Australia
2018 Dx RC
G2 EMVI LVI, 4 liver mets
pT3N1aM1a Stage IVa MSS NRAS G13R
CEA 14>2>32>16>19>30>140>70
11/18 FOLFOX
3/19 Liver resection
5/19 Pelvic IMRT
7/19 ULAR
8/19 Liver met
8/19 FOLFOX, FOLFOXIRI, FOLFIRI
12/19 Liver resection
NED 2 years
11/21 Liver met, PALN, lung nodules
3/22 PVE, lymphadenectomy, liver SBRT
10/22 PALN SBRT
11/22 Liver mets, peri nodule. Xeloda+Bev
4/23 XELIRI+Bev
9/23 ATRIUM trial
12/23 Modified FOLFIRI+Bev
3/24 VAXINIA (CF33 + hNIS) trial

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beach sunrise
Posts: 1041
Joined: Thu Mar 05, 2020 7:14 pm

Re: Prenuvo

Postby beach sunrise » Sun Aug 29, 2021 2:49 pm

You are probably correct. After further study of it and asking for more info as a CRC patient about detection of mets I haven't heard back yet. The 7T MRI is the best I have found so far that beats SOC scans but its an experimental at this time for CRC patients so its very hard to qualify. Mainly used for brain and knees, go figure.
8/19 RC CEA 82.6 T3N0M0
5FU/rad 6 wk
IVC 75g 1 1/2 wks before surgery. Continue 2x a week
Surg 1/20 -margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
pre cea 24 post 5.9
FOLFOX
7 rds 6-10 CEA 11.4 No more
CEA
7/20 11.1 8.8
8/20 7.8
9/20 8.8, 9, 8.6
10/20 8.1
11/20 8s
12/20 8s-9s
ADAPT++++ chrono
CEA
10/23/22 26.x
12/23/22 22.x
2023
1/5 17.1
1/20 15.9
3/30 14.9
6/12 13.3
8/1 2.1
Nodule RML SUV 1.3 5mm
Rolles 3 of 4 lung nodules cancer
KRAS
Chem-sens test failed Not enough ca cells to test


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