phase 1 first in human

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jep
Posts: 260
Joined: Sun Jun 11, 2017 7:45 pm
Location: New England, USA

phase 1 first in human

Postby jep » Thu Oct 10, 2019 10:19 am

Hey everyone . . . so my husband got a spot in a phase 1 "first in human" clinical trial. This is both exciting and nerve wracking . . . we just got the paper work and I need to read through everything and do some research. Just wondering if anyone has experience with a "first in human" trial . . . his will involve ABBV-151 and ABBV-181 (?). There are 2 parts to this study, and each patient is only enrolled in one. Just reaching out to see if anyone has any advice/experience to share. Thank you all!
jep
Stage IV CC 5/16/17
Loc: recto-sig
Type: Adenocarcinoma
Size: 7.4 cm
Grade: G3
TNM: T3N2M1
LNs: 8/20
BL CEA: .9
LVI: present
Perineural invasion: present
LAR margins: clear (w/in microns)
Folfox (8/17-1/18)
Scope 6/18 - CLEAR! - 2 polyps
PET 10/17/18: 3 pos LNs
Irino + Vecti (11/18)
CEA: 1.7 (2/19)
Xel + rad (5/19)
Surgery: 8/21/19 (aborted)
P1 Trial 10/19 - 12/19
Bypass 12/6/19
Folfox + vecti 1/2/19 - 4/3/20
Kid Fail 5/1/20
Folfiri + Avastin 5/20 - 6/20
bypass 6/29/20
Stivarga 7/18/20 -
Home 9/10/20

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