tammylane wrote:If you are interested it is a blend of liquid amitriptyline, ketoprofen and lidocaine
the quick hit will be the lidocaine and a GOOD transdermal formulation (PLO ? )... IMO ! to enhance absorption and local/blood levels ASAP
I've used these a lot, especially for cats ... who HATE to take pills and their owners who hate giving cats pills ..... even MORE !
the secret for the amitriptyline is maintaining blood levels ( also true of gabapentin, amantidine and pregabalin ) as it is more a "neuropathic" medication as opposed to an opioid analgesic or NSAID
we take the latter for pain right here right now and they are CNS and receptor based
the neuropathics are acting more at the nerve root / local reflex / spinal pathway level
which is why multimodal analgesia is almost ALWAYS more effective than single mode therapy ... NOT JMO !
They are the only things which can address allodynia and some "wind-up" phenomena where things which "should" only cause a little pain reaction can cause catastrophic escalations of pain responses in some patients.
GLAD you have a doc who is willing to go "beyond" and keep tweaking things until the problem is SOLVED.
Just as another FYI on topic
in this thread :
when oral and topical meds actually do not give sufficient pain relief ... there could be a consideration for nerve/nerve root ablations by a pain/neuro specialist trained in such things, to actually "kill" the nerve causing the problem. Won't be used as a first choice and many docs won't consider it ... BUTT then they are not the ones suffering from intractable pain
Just something to keep in mind for certain situations.
Yes, I have first hand experience with this.