Jolene wrote:I hope this isn't too late.
I'm not familiar with the concept of using signatera for CCR management so I can't really comment. My doctor who is very pro WW has never mentioned this method of managing before and I don't think I've come across any research that uses signatera to make judgment of whether one should proceed with WW or not. How did you come about with this idea? Did you read about it somewhere?
You can see from my signature that my doctor basically uses MRI + scope check (for site check) + biopsy to triangulate the positive results once every 3 months in the first year of WW. It was then spaced out to once every 4 months and now in my 2.5 years in of WW, it is being spaced out to once every 6 months. PET was also done as regularly as possible ( once every 9-12 months) to keep track of any stray cancer cells in the body.
A lot of us here have low CEA that are unreliable and I believed that has never been a good tool for WW to begin with. I'm not familiar with signatera but my feeling is that you can't beat a management that includes MRI + scope (and biopsy) + PET scan on regular basis. Hope this helps.
I don't believe what i described is an accepted protocol, at least not by my oncologist. It just made sense to me that signatera could be used in addition to the regular WW protocol. On this board some have already gotten the test and it seems to affect the frequency of the watch part. When you say doctor in your case, is that your surgeon or your oncologist. My surgeon is very anti-biopsy, not sure why.
I agree with you on the MRI/Scope and Biopsy, i believe that's the right approach. I was looking at Signatera as a replacement for CEA since CEA is not super reliable.