Big pharma overstating benefits and ignoring side effects and negative data. Who would of thought?
However, I'm not sure that it even counts as a Faustian bargain for 2nd and 3rd line patients, rather "just" a reduction in benefits, unless the long term effect is even uglier than the original spiral down and out.
My biggest question is whether some of the supplements and generic drugs could eliminate or control some of the early secondary cancer cell lines, because there are clear cases and series of lab experiments where vitamin C and/or K2 bought time or remissions in established leukemias. (but not too soon if there is interaction with the CAR-T treatment itself and generic)
Rock_Robster wrote:but I’m not aware of any conventional cancer treatment that doesn’t cause increased risk of secondary cancer.
This even applies to scans with Xrays and PET-FDG, and other effects for contrasts.
However there are huge differences between families of chemo for cancer risk e.g. 5FU is not nearly as bad as some others. This actually came up with blood monitoring for my wife where chemo activity indication of increased chemo-cancer inhibition effectiveness correlated with increased secondary cancer risk 3 years later for some Pt combination drugs for other cancers (but not 5FU). e.g. screaming down the race track at 126, "more chemo" and better, when other drugs crater you later at 115...