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by rp1954
Sat Nov 27, 2021 5:06 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Immunotherapy in Switzerland
Replies: 46
Views: 5778

Re: Immunotherapy in Switzerland

Trying to resummarize this cimetidine discussion for later readers First, I don't promote this trial. I provided it as counter-evidence to the Matsumoto trial. I'm not claiming either trial is better or worse. I'm saying we don't know which trial to believe. The two trials are very, very different: ...
by rp1954
Wed Nov 24, 2021 1:35 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: HFS symptoms
Replies: 8
Views: 781

Re: HFS symptoms

The best preventative of HFS from xeloda that I've heard of, is IV vitamin C. In a Riordan Clinic case study, a IVC + xeloda patient who didn't have HFS symptoms went on vacation. After some missed IV vitamin C infusions, they began to have HFS a week or so later. The HFS went away when the IV vitam...
by rp1954
Wed Nov 10, 2021 2:30 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Interested in chronomodulated Xeloda
Replies: 14
Views: 1531

Re: Interested in chronomodulated Xeloda

I certainly would be interested to see the series of markers, inflammation markers and cytokines that you have to date vs doses. We have very little inflammation data presented as yet, and Block Center certainly could use more definition as an option here. As for adjuncts for BRAFv600 I might try to...
by rp1954
Tue Nov 09, 2021 2:06 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Interested in chronomodulated Xeloda
Replies: 14
Views: 1531

Re: Interested in chronomodulated Xeloda

Hi All, We have been doing chronomodulated chemotherapy, with 6 vitamin infusions along with Folfoxiri+Avastin. My husband has had a great response. They can't even find the lesions on a PET. We were offered oral Xeloda and 5FU. My question is does anyone here do Xeloda and 5FU chronomodulated? Als...
by rp1954
Sat Nov 06, 2021 1:00 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Bladder cancer forum?
Replies: 4
Views: 1379

Re: Bladder cancer forum?

Bladder cancer is one of the cancers with cell lines particularly sensitive to high dose vitamin C, even solo.

I would check out the Riordan Clinic on IV vitamin C as an additive adjunct for bladder cancer.
by rp1954
Tue Oct 19, 2021 12:17 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Liver enzyme spike after adjuvant chemo
Replies: 10
Views: 2791

Re: Liver enzyme spike after adjuvant chemo

When were her previous, first and last metabolic panels done? You might post the side by side comparisons. It's a commonplace that many panels are trashed following 12 cycles of actual Folfox or Xelox at maximum tolerance dosing. Some panels can be permanently shifted or altered but most settle down...
by rp1954
Wed Oct 13, 2021 5:01 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Possible new recommendations on less Aspirin use
Replies: 10
Views: 4011

Re: Possible new recommendations on less Aspirin use

I consider the media howl likely part of the normal pincer movements to remove or restrict cheap therapies. First, comes the academic cautionary notes to pose a problem, sometimes in some ignorant or cocked way, carefully avoiding solutions and inconvenient facts. Tsk, tsk, tut, tut. Then comes the ...
by rp1954
Mon Oct 04, 2021 5:29 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Xeloda med concerns and timing
Replies: 24
Views: 4956

IVC and HFS

Although there was not much literature on it, patients have been using IV vitamin C to make their chemo tolerable for a long time. I've known mCRC patients at the point of quitting Folfiri that gained 2-3 years chemo by IV vitamin C. I have to note tolerance is different than improved chemo performa...
by rp1954
Mon Oct 04, 2021 2:19 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Xeloda med concerns and timing
Replies: 24
Views: 4956

Chronomodulation

Chronomodulation of Xeloda is new and unknown to most drs and oncologists. What I've seen suggests its potential usefulness. UFT prescribing doctors had a lot more experience with a simple version. We had no problems with a chronomodulated UFT version of ADAPT monitored for liver stress, plus lots o...
by rp1954
Mon Oct 04, 2021 2:05 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: Xeloda med concerns and timing
Replies: 24
Views: 4956

Folic acid

Remove folic acid from your diet and have natural folate sources. Folic acid and 5FU compounds are toxic to varying degrees in different people, 50% of the population seriously affected. This has been discussed several times before. This is probably a big part of the Xeloda dose difference between E...
by rp1954
Fri Oct 01, 2021 5:47 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: stage 4 with extensive lymph nodes involvement
Replies: 26
Views: 4534

Re: stage 4 with extensive lymph nodes involvement

For my wife's biochemistry, we did not need Avasatin (mab antibody for VEGF-A) because we were able to attack the precursor of VEGF-A directly to destroy excess precursor and indirectly to reduce precursors formation in one common major cancer process, where the chemical has side benefits with 5FU d...
by rp1954
Thu Sep 30, 2021 2:07 am
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: stage 4 with extensive lymph nodes involvement
Replies: 26
Views: 4534

Re: stage 4 with extensive lymph nodes involvement

Bloodwork is what I struggle with, being stuck all the time is no fun, ha. This is actually a common symptom of too much interference like insurance or lack of coordination/cooperation of drs. Blood draws were easy for us, one and done with home service; less frequently as we were cumulatively succ...
by rp1954
Tue Sep 28, 2021 11:08 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: stage 4 with extensive lymph nodes involvement
Replies: 26
Views: 4534

Re: stage 4 with extensive lymph nodes involvement

The blood tests provide initial information and on going information both benefits and toxicity in realtime. We always aimed for low toxicity and took blood data frequently. We worked with doctors to prescribe everything. Common, mild drugs are a lot different than normal chemo. Most things are wate...
by rp1954
Sun Sep 26, 2021 8:52 pm
Forum: Colon Talk - Colon cancer (colorectal cancer) support forum
Topic: stage 4 with extensive lymph nodes involvement
Replies: 26
Views: 4534

Re: stage 4 with extensive lymph nodes involvement

mm data are direct measurements on the nodes, a few seconds per "shot" about like a game video. Size may be more important than SUV, so a better list is advisable. Each consulting center that looks directly at the CT images can do it very fast, I've listened while the radiologist did it. J...

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