I didn't intend to be rude, but the conclusion of the article that orange colored fruits and vegetables were somehow bad for males might or might not be good information, and could cause someone to eliminate them without solid evidence. I didn't see much evidence they'd investigated that very thorou...

To me, that paper is an example of why reliable guidance on diet is so muddled. Most of it was consistent with well-known evidence that eating more fruits and vegetables is good. But trying to distinguish effects of different colors seemed problematic to me. Some of it didn't make any biological sen...

He may have had something called "early postoperative SBO" from the adhesion surgery. Those new adhesions usually are soft enough to clear with conservative management. It's not rare but it's not common either. So we wait. Unfortunately he has progressed while off chemo and even if this cl...

Good luck, keep us informed.

He is back in the hospital with another blockage. It may be due to manipulation of a bowel that was apparently very tangled with scar tissue. Hopefully your situation will not be as bad. The bypass was successful and that's open, this is nearby and new but may resolve.

We just got the bad news of liver spots. I am hoping he will be a candidate for RFA (I doubt they would do resection due to the lymphatic spread).

Complete responses to chemo are a few percent, maybe 5% at most, of patients, which isn't zero but isn't very good odds.

Hi Rob, Speaking as a proponent of evidence-based medicine (with a scientific background) the problem is that a lot of what is known about diet is highly controversial and changes frequently. It is very difficult to do high-quality research with diet, largely because it's nearly always retrospective...

Good luck, Riki, this has been rougher on my husband than his original surgery and we're still not in the clear since he is still having problems.

I'd rather not say where we live. It was a medical school-affiliated teaching hospital. The same surgeon who did the original surgery did this one. They didn't use any barrier film as far as I know. I think they normally just leave the bypassed bowel in situ. It presumably still has its blood supply...

I also had Shingrix a year or two ago and the second shot knocked me flat (way worse than either Covid vaccine) but I would rather not get shingles so didn't mind.

It's consistent with emerging data that immunotherapy should probably be first-line treatment for MSI-H. I'm not sure whether the sample was large enough to say whether celecoxib added anything or not. They didn't seem to be comparing it to Folfox or such. Now if only somebody could come up with a c...

He just got out of the hospital yesterday. It was fairly grueling, a full open surgery (they just reopened the old incision). Nearly a week of paralytic ileus. But in the last few days he's been improving rapidly, his appetite is returning and things seem to be moving much more smoothly. He ended up...

Platelet inhibition *may* be helpful for colorectal cancers since at least some of those seem to travel through the bloodstream with platelet "escorts" to protect them, but whether regular aspirin use would be the solution for that issue seems to be quite unclear and the side effects may o...

Given that history of extensive pelvic surgery, have they checked for ureteral strictures due to scar adhesions? (That wouldn't usually account for liver problems, however.)

Riki, have they scheduled surgery for you yet? DH's was yesterday and it was more extensive than they'd expected. He had significant scarring and had to have a bowel bypass. Obviously it was never going to resolve long-term on its own. No sign of new or unknown cancer, it was all scar tissue consist...