Bpaint wrote:He has no colon cancer in his family and he is overall very healthy besides the cancer. He ran 15 miles the week before his diagnosis.
We are in Madison, WI at the carbonne Cancer center. As far as I know, he hasn’t gotten a foundation 1 test.
Bpaint wrote:My husband (age 41) was diagnosed with stage 4 colon cancer on August 31. His primary tumor is in his sigmoid colon, and he has more tumors in his liver, lungs and distant lymph nodes. His CEA number was 713. He has now gone through 2 rounds of folfox + avastin. He had to skip his last round because he developed pneumonia and his immune system numbers were too low. Hopefully they will be up this week so he can start treatment again.
We are feeling sad and overwhelmed. We have two little kids (ages 3 and 6), and my husband wasn't having any pain or symptoms, just some bleeding that his primary doctor said he was 99% sure was hemorrhoids. I found this message board in trying to research information about whether there is anything we can do in addition to the chemo that would help my husband's chances. I've been reading through some of the posts on here, and there is a lot of information, but it is hard to tell whether it applies to him. It seems like the usefulness of things like supplements might depend on what type of cancer it is? The only information we have from the pathology report is that it is "low probability of msi-h." But there is no information about mutations or anything like that.
I am wondering whether anyone else had to wait a long time to get the results from genetic testing? His oncologist said he was ordering testing on the tumor, but it has been about 6 weeks now and we still haven't heard anything.
Bpaint wrote:After bugging the oncologist about the testing results, I finally got a copy of them. The results say that my husband's tumor is MSS, low TMB, with mutations in APC, PIK3R1, and TP53. No mutations in KRAS or BRAF. Based on what I've read on this message board and elsewhere, this means that the cancer wouldn't be responsive to any known targeted therapies, like immunotherapy, right?
I want to get a second opinion about treatment, but my husband is hesitant because he is worried that we wouldn't know what to do if the second opinion recommended something different from his current treatment.
Bpaint wrote:After bugging the oncologist about the testing results, I finally got a copy of them. The results say that my husband's tumor is MSS, low TMB, with mutations in APC, PIK3R1, and TP53. No mutations in KRAS or BRAF. Based on what I've read on this message board and elsewhere, this means that the cancer wouldn't be responsive to any known targeted therapies, like immunotherapy, right?
I want to get a second opinion about treatment, but my husband is hesitant because he is worried that we wouldn't know what to do if the second opinion recommended something different from his current treatment.
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