Postby lovelife789 » Mon Sep 14, 2020 6:00 am
Internal1 wrote:Hi All,
Today I had my 8th cycle of folfox and avastin and I had a hypersensitivity reaction to oxaliplatin just 15-20 minutes after infusion started. They had to stop chemo and I was given Benadryl and steroids. The fellow who came to see me called my oncologist who decided to only continue with Leucovorin and they connected the 5fu to come home with it. The fellow is not sure what the oncologist will do for my next cycle. Did anyone have an allergic reaction to oxaliplatin and if they did what did your oncologist do? Did they pre-medicate you with Benadryl and steroids? Or did they slow down the infusion? Or did they stop it completely? Thank you all!
Hi,
I did have a severe allergic reaction to oxi. What they did was not stopping it altogether. They gave me a break with Benadryl and steroids. Then, slow drip for the rest of the infusion. From that time onwards, they gave me steroids to take before the infusion, during and for the 3 days 5FU infusion just in case. It went well, I finished all 12 at last without any issue.
Hope it helps.
Lovelife
F/38 - Dx 8 Mar 17, CEA 189.5
Stage IV Sig. Colon, Liver mets, T3N0M1a, KRAS NRAS Wild
3/17- 6/17 - 6 x FOLFOX + Erbitux
7/17 - 1st & 2nd Liver resec
9-12/17' - 13 x FOLFOX
1-6/18 - NED
6/18 - PET SCAN showed a 0.8mm lung nodule, VATs
8/18 - 4/19 - NED
5/19 - recurrence 1 x PALN, 1x common iliac
FOLFIRI + Avastin x 12 - complete response, SBRT
12/19-5/20 - NED
5/20 - recurrence in LNs, tiny liver spots x 2, W n W due to COVID
8/20 - LNs very slightly increased, liver stable, one new liver spot