update on my dad and advise?

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Joined: Wed Apr 03, 2019 11:40 pm

update on my dad and advise?

Postby natelaugh » Thu Oct 17, 2019 8:59 pm


5FU monotherapy didn't work for my dad. Cancers have spread all over his lung, lymph nodes and one on liver. The oncologist will give my dad a regimen of 5FU, avastin and oxaliplatin at 70% for all 3. After 3 months, remove oxaliplatin and stay with 5FU and avastin. So 3 months with 3 chemo follow by 3 months of 2 chemo and repeat.

Any advise on what to look for to see if it works? Or anyone try this 3 combinations?

I hope everyone is doing well !!


Oct 17, 2019
PET/CT scan
1. Hypermetabolic adenopathy above and below the diaphragm to include left supraclavicular "Virchow's node," and a dominant mesenteric mass in the right mid abdomen.
2. Bilateral FDG-avid lung parenchymal metastasis.
3. Probable solitary liver parenchymal metastasis in the right hepatic lobe.
4. No FDG-avid osseous lesions.
Caregiver to 80M
11/2018 rightPain
1/19/19 scopy,path
1/23 CTscan
2/19 surgery
2/26-2/28 NGTube
2/28-3/14 TPN bc ileus
3/2 2nd surgeryCloseOpenWound
3/4-3/28 woundVac
size: 6cm Adenocarcinoma
grade Poorly
Stage IIIC T3N2aMx
Surgical margins:clear
MSI:MMR (MLH1, MSH2, MSH6, PMS2) Intact nuclear expression
Lynch status:N
Laparascopic, partial colectomy
CEA:3/28/19 2.8
Chemo:4/16/19-9/17/19 5FU,12cycles,every 14days,leucoverin,zofran,Dexamethasone

Posts: 386
Joined: Tue Mar 12, 2019 2:41 pm
Location: Montana

Re: update on my dad and advise?

Postby Claudine » Fri Oct 18, 2019 11:52 am

I'm so sorry that monotherapy did not work for your dad. I do not have any experience with the regimen prescribed, but at least there's a plan of action! Hopefully the combination of drugs will be more successful, and not too hard on him. Best of luck XXX
Wife of Dx 04/18 (51 yo). MSS, KRAS G12A
No primary (involuted?)
Lytic tumor L4 vertebrae, EBRT 04/18, SBRT 02/19
Resect small intestine 05/18 (no cancer - Crohn's)
Failed adjuvant Xelox
Folfiri + Avastin 03/19 to 01/20
6.7 cm left adrenal mass 03/19, successful resection 02/20
CEA since 03/19: high 58, low 3.2, now 4.4
Scan 03/19: Multiple small lung nodules up to 5mm
Scan 12/19: one 1mm stable nodule
PET 04/20 uptake by L4
L3-L4-L5 fusion surgery and residual tumor removal 05/20

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