Wanted to post about my day at Duke Cancer Center today. I guess for a bit of encouragement and support. But also, in case any of this information is helpful to others.
Last Wednesday, 11/21/18, I had a CT scan after 4 rounds of FOLFOX + Avastin. Note that I had 6 rounds of the same between 3/18 and 5/18 before I had my liver resection. Scan shows there are two new liver lesions. And there is slight growth on two existing liver lesions. In addition, CT scan showed an inflamed lymph node next to my aorta. However, the mild tissue around the peritoneal lining that showed up in the PET scan back in September is not visible on this CT scan.
In summary, my onc suggests we’ve reach the end of the line with FOLFOX. She explained that this is not out of the ordinary. And since I had a dramatically good response to FOLFOX initially, she expects positive results moving to FOLFIRI. As such, I am now registered to start a Phase II clinical trial beginning December 10th 2018. I will either be on the control group receiving FOLFIRI + Avastin. Or, I’ll be getting FOLFIRI + ABT-165, a new drug from AbbVie that is being tested for better efficacy than Avastin.
I also received my Foundation One CDx results today. The genomic findings are as follows:
Other alterations and biomarkers observed included:
Duke has been working with Memorial Sloan Kettering and Dr. Kemeny to begin HAI pump treatment here in North Carolina. But right now, because of the lymph node inflammation (which is believed to be disease), I don’t qualify for it. Hoping that after a few rounds of FOLFIRI this changes.
Finally, I’ve been taking supplements as I work with a naturopathic doctor. It’s only been two months. So, hard to say if it’s working or not. But, for what it’s worth, I’m taking Curcumin, Fermented COD fish oil, Sulforaphane Glucosinolate, Modified Pectin Citrus, Vitamin D, Conium Maculatum, and loads of green tea.
I’ll update my signature shortly. But appreciate any input / feedback from anyone with similar circumstances. Good news is that for now, I feel amazingly good except for 2-3 days during chemo week. So, on I go living my life and trying to turn any possible stone that will keep me on this earth with my friends and family for as long as possible.
42 yr, male, husband and father of 3
DX Stage IV Colon Cancer Jan 2018
Multiple liver mets
KRAS G13D / MSS
Jan 2018 Partial colon resection
Mar 2018 FOLFOX + Avastin | CEA 60.1
July 2018 Partial liver resection | CEA 4.7
Sep 2018 Recurrence in liver | CEA 2.9
Oct 2018 FOLFOX + Avastin
Nov 2018 Stopping FOLFOX. New mets | CEA 4.3
Dec 2018 Beginning AbbVie ABT-165 Trial