Katrinaks24 wrote:... I see most posts about folfiri and folfox, but not about folfoxiri. Can anyone share their experiences?
FOLFOXIRI: Irinotecan 165 mg/m 2 over 60 minutes then oxaliplatin 85 mg/m 2 plus leuovorin 200 mg/m 2 concurrently over 120 minutes then 5-FU 3200 mg/m 2 over 48 hours; repeat every 2 wk for four to six cycles.
Reference:
Falcone A, Masi G, Brunetti I, et al. The Triplet Combination of Irinotecan, Oxaliplatin and 5FU/LV (FOLFOXIRI) vs the Doublet of Irinotecan and 5FU/LV (FOLFIRI) as First-Line Treatment of Metastatic Colorectal Cancer (MCRC): Results of a Randomized Phase III Trial by the Gruppo Oncologico Nord Ovest (G.O.N.O.). Proceedings from the 42nd Annual Meeting of the American Society of Clinical Oncology. Atlanta, Ga. June 2006. Abstract # 3513:
Katrinaks24 wrote:Surgeon at USC Keck was not able to complete surgery because the discovery of mets. Treatment plan is folfoxiri with Avastin. Port placement on Wednesday and chemo on the 15th. The goal is to get to the point of being able to have surgery with HIPEC. I see most posts about folfiri and folfox, but not about folfoxiri. Can anyone share their experiences?
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