Sharing Hope wrote:Thank you, so much, for all your time and helpful posts, NHMike!
I didn't realize that tumor mutation testing isn't protocol - wow. Pretty critical in treatment plans, I'd say.
Glad to hear you had a successful surgery. How is your recovery? Was it laporoscopic?
Though my surgery is scheduled, they wanted to shrink my tumor with chemo - it's on the large side 2+". It hasn't shrunk but they'll take out my entire left lobe.
I hope your recuperation continues to go well and you beat this fully!
My surgery was Laparoscopic Assisted LAR so it was an open surgery and the surgeon indicated this in the pre-op meeting. So recovery is a lot slower than I'd like but I was able to take a 0.6 mile walk this morning (normal days I may walk/run 5-10 miles).
2 inches is definitely large and it's going to put pressure on something. I had some pain from mine which was over 100 cm^3 or over 6 in^3 and I had this fear that I wasn't going to be able to go to the bathroom at all because it was getting so big. I can understand the worries about a large tumor.
Some ideas for papers that I thought up this morning:
* It would be interesting to write a paper to make the case for Genomic Tumor Testing on Colorectal biopsies for Rectal Cancer or tumors for Colon Cancer. The case could be made for patients with KRAS so that they shouldn't use Anti-EGFR drugs and BRAF so that oncologists know that there is time pressure and that they're dealing with an aggressive cancer that may not respond well to traditional front-line chemotherapy.
* It would also be interesting to write a paper describing all of the known mutations of Colorectal Cancer, their prevalence, survival rates, response to front-line Colorectal Cancer chemotherapy and targeted therapies. Depth would be a variable for the paper. It could go into the technical details of how the mutations and variants work or it could just be upper-level numbers. Or there could be two papers overall, one with statistics and the other describing the mechanisms of the know Colorectal Cancer mutations.
I will keep an eye out for your comments as your surgery date approaches.