My husband Nitesh is 27 yo, KRAS Wild (normal), BRAF not mutated, MSS Rectal cancer with primary resected with recurrence in bilateral Lung Mets, Tailbone, Abdomen and Prostate mets. Within 15 days of his last 12 cycles of FOLFOX his unresected disease metastasized and largest tumor size out of 12 tumors is 5x4x4 cm. Currently he is getting FOLFIRI with PANITUMUMAB as Target agents. His Doctors have told that this is incurable.
We are searching for Clinical trials with our limited knowledge and his current med oncologist at India is not familiar with specific trials or alternative options available. Kindly suggest suitable clinical trials for him, since he's MSS.
A little background on my husband: He was diagnosed last year with stage III Rectum cancer (4 out of 15 nodes positive) in June of 2016 at the age of 26. He had Radiation therapy followed by APR Surgery and 12 cycles of FOLFOX (Oxaliplatin) which ended in May 2017. Unfortunately, after 15 days in the next scan, he had 12 tumors in bilateral lungs, abdomen, prostate, tailbone and colostomy region. Radiation and surgery are out of options for him.
Please suggest suitable trials for my husband.