There's information that likely won't be known immediately about the mets, and information that is typically missed (e.g. some of the blood work). Completeness and accuracy develop with time, and effort.
The decisions we have made with many unknowns included steps like IV vitamin C after surgery, and alternative adjuncts including heavy duty nutrients to recover faster, and second time around, to begin metronomic chemo sooner, much sooner. In the US, Dr Lin's regimens, with capecitabine (an oral 5FU drug) + celecoxib, have been pretty much the only metronomic regimens available.
I notice that milk whey protein got the blame for liquid meal replacement formulas' indigestion in earlier discussions. At least in 2008-2010, these formulas used casein for their protein, a much different proposition. We made a decision to totally overhaul the formulas and use whey protein for cancer post surgery and replace the oils with coconut oil (+ some EV olive oil, EPO - Evening Primrose Oil, and nonrancid fish oil) in the formula, along with tons of vitamins and nutrients selected from the alternative world.
Since we were highly dissatisfied with the answers we initially got on chemo, let me brief you on what we found then after a hard eyed search. For metastatic colon cancer, chemo is essentially a necessity. The real issue is what treatment - which adjuncts, conventional and alternative, for the particular cell phenotypes and real estate involved.
From the conventional oncology world, we retained an oral 5FU drug from Asia applied metronomically (3x daily) and dumped the rest but with a realistic commitment to performance (inexpensive extra tests). The part where it gets a little trickier, are the nonstandard adjuvants that are milder than say, irinotecan and oxaliplatin, but need to be well chosen to achieve the treatment intensity inhibit or kill cancer cells, especially the particular cancer stem cells. Beyond perhaps, cimetidine, aspirin, celecoxib, vitamin D3, and PSK, conventional oncologists are not likely to even entertain anything else, if at all. Support there is typically with separate complementary medicine doctors, DIY or both.
With the right choices, we were able to get chemo in sooner, longer, with more success, with more comforts.
watchful, active researcher and caregiver for stage IVb/c CC. surgeries 4/10 sigmoid etc & 5/11 para-aortic LN cluster; 8 yrs immuno-Chemo for mCRC; now no chemo
most of 2010 Life Extension recommendations and possibilities + more, some (much) higher, peaking ~2011-12, taper to almost nothing mid 2018, mostly IV C