Thanks, Liz. I am still learning what MSI is, and how that might affect treatment. There is just so much new information and often its contradictory information. For example, I have read that chemotherapy is needless in cases of stages I to II CC and for stage IIIA CC with low risk of recurrence, such as node positive T1/T2 patients. (https://wjso.biomedcentral.com/articles/10.1186/1477-7819-12-145
) Elsewhere, I have read that it's standard for all stage IIIs and even for stage II.
My understanding with stage III, standard protocol is chemo. With stage III, you have cancer cells in your lymph nodes. You REALLY want to kill them off before they can find a new home in another part of your body like your liver or lungs. The difference between A, B, C, is the number of nodes effected, butt the fact still remains you have cancer cells in your body that you REALLY want to kill off with chemo.
Stage II can be a grey area, then you need to consider how deep the tumor went, how aggressive the cancer cells are, etc. If you are a stage II, I would HIGHLY recommend a 2nd opinion at a major cancer treatment center, because it can be a grey area. You want the latest greatest research giving you an informed opinion. Not something that is 5-10 out of date.
Please remember you've only got one chance to get it right the first time, you want to give it 110% the first and not look back with regrets.
mpbser wrote:I just got the book Cancer: Out of the Box but I am a little hesitant to read it. I don't want to feel at odds with my doctors because I fear alienating them might jeopardize my care. I have found over the years that many doctors can be very threatened when presented with data that contradicts their paradigm.
This is your life, you need to be your own advocate and if that means asking a lot of question, DO IT!!! If your Dr can not deal with your researching & presenting other options, maybe it's time to find a new Dr. Not all doctor are up to date on the latest procedures. Remember, not all Dr graduate at the top of there class, some are better than others.
There are many survivors here who were told they only have a few months or a few years to live. Yet many of them are NED today because they did there own research and being their advocate.
Sleen's journey is just one example.viewtopic.php?f=1&t=49736
Hope this helps, all the best,