Elizabeth thanks so much for replying.
I had my third & last cyber knife RT session yesterday. After about 6 hours the same thing happened: bloating, discomfort, cramping. Today (36 hrs later) it's way better.
In case anyone else undergoes the same combination of immuno + radio, my docs don't seem concerned. They reckon it might be evidence of an abscopal effect taking place (good) or the RT causing irritation to my bowel, being adjacent to the target lesion, leading to colitis, cramp etc (neutral).
Scans in 8 weeks to determine effectiveness, if any. I'll update then.
05/15 L hemi-colectomy
05/15 Dx st 3 T4N2M0 @43
kids: now 13, 10
BRAFm mucinous - KRASw
06/15 liver mets
06/15 CEA 9, CA19-9 400+
06/15 - 09/15 6 x FOLFOXIRI+Avastin
09/15 markers 4/50
10/15 drain-site met
1-8/16 BRAF triplet (dabrafenib, panitumumab, trametinib)
CEA;CA19-9: range 16;650 to 1;36 back to 4;135
10/16 Trial: NCT02650713
Trials: anti-GITR then ERK inhibitor
6/18 progression, back to chemo
Current: 12 rounds of folfoxiri + avastin