aja1121 wrote:My husband and I met with an oncologist at Mayo Clinic on March 20 regarding BBI608 and FOLFIRI +/- Avastin. Oncologist told us there are currently 91 open slots in the trial nationwide. He also said that in initial Phase I trials a few years back, the side effects of BBI608 were so harsh he had little hope for the drug. He now feels very positive about the results they are seeing, and said they seem to have found the "sweet spot" for dosage in terms of limiting side effects.
Most recent scan last week showed control/minor shrinkage on Xeloda/Avastin, so we are sticking with that for now and keeping trial in our back pocket. Just thought I'd share for those interested.
(Trial info again, https://clinicaltrials.gov/ct2/show/NCT02753127)
Thanks for the info. I had heard the side effects were similar to Folfiri alone and I hope it's true.
I got the trial nurse at one of the centers to take my records finally, so I guess I'm on the road to finding out if I will be in this trial. Fingers crossed.