Postby DK37 » Sat Mar 19, 2016 7:25 am
Here is a MSS Trial that has been open for awhile but I don't see a post from me listing it (unless I'm blind always possible
)
It combines Anti-CD27 (Varlilumab) with Anti-PD-1 (Nivolumab).
There is good preclinical data in mice and I have heard some recent (unconfirmed) buzz on this one. It has sites nationwide.
https://clinicaltrials.gov/ct2/show/NCT02335918Cheers,
-DK
6/4/2012 Dx Stage 3C CRC @ 40 yo. MSS, KRAS-WT, BRAF-WT, p53-mut
7/12 FOLFOX/FOLFIRI
2/13 NED!
8/13 Enlarged lymphs - Stable
10/14 Stage IV. Lung & Lymph mets. 5-FU+bev
3/15 Cetuximab
11/15 FOLFIRI + bev
11/16 Signs of FOLFIRI resistance (Lymph mets)
1/17 Palliative radiation for resistant mets
2/17 FOLFIRI + bev + Maraviroc (off-label)
3/17 FOLFIRI + Erbitux + Maraviroc (off-label)
MSS-CRC Clinical Trial Finder: http://trialfinder.fightcrc.org/2016 Colondar 2.0 ModelDK37 Science Posts List