Mike, if you choose Xeloda, but want to be as aggressive as possible, as a stage 3, of course you'll need to add Oxaliplatin. It can be given intravenously, but can be really hard on the veins. I can attest to the fact that it was hard on my veins via IV, but much easier via the port. If you have any issues with reflux and routinely take PPI's (Prilosec, Nexium, etc), you're not a candidate for Xelox. There was an article presented at the ASCO meeting last May indicating that PPI's interfer with the absorption of Xeloda. Unfortunately, we did not know that when I started my chemo last June. After two horrid rounds when I could not complete of Xelox, at the prompting of another member here, I started researching PPI's and Xeloda. That's when I found the article and presented it to my Oncologist. We switched to Folfox and did fine. I only needed an occasional Zantac to control the gastric upset.
Sorry for the book and the soapbox. I just don't want anyone else to go through any unnecessary pain and ineffective, ill-absorbed Xeloda!
Good luck to you, Jane
Last edited by Ajane
on Tue Mar 22, 2016 11:29 pm, edited 6 times in total.
7/13, T2, G3, Ultra-low. CEA 5.7 KRAS Wild, MSS
8-9/13 6 wks Xeloda/radiation
12/13 TEM pCR NED
5/15 CEA 4.6 PET 1.5 cm met, UL Lobectomy
6-10/15: Rounds 1-2 Xelox+Avastin; 3-8 Folfox+Avastin
10/15-4/16: 12 rounds Avastin
9/2016 CEA 4.2, 12 mm AP node
11/2016 CEA 4.3. PET/CT. 16mm AP nodal met removed
4 wks chemorad
2/2017 NED CEA 2.4
Carafate to tx esophageal ulcers caused by rad
Avastin maintenance postponed
2 Corinthians 12:9