Following up on StephenWinsToday’s post viewtopic.php?f=1&t=52986
In addition to strong synergy with PD-1 pathway inhibitors, note this observation: http://www.uchospitals.edu/news/2015/20 ... erapy.html
"By introducing a particular strain of bacteria into the digestive tracts of mice with melanoma, researchers at the University of Chicago were able to boost the ability of the animal's immune systems to attack tumor cells. The gains were comparable to treatment with anti-cancer drugs known as checkpoint inhibitors, such as anti-PD-L1 antibodies."
That is a very profound observation that requires the scientific scrutiny of repeatability by other labs to confirm (that is the way science works - one reason PD-1 inhibitors were such a HUGE scientific leap for the concept of immunotherapy was that not only were their effects large but also very reproducible between labs). But while scientists work out the details and confirm, due to the low side effect possibility, I'll be taking...
Paper from the Journal Science: http://www.sciencemag.org/content/early ... ce.aac4255
-DK37