Grapefruit and its juice is contraindicated for Lipitor and most other statin drugs, used for cholesterol control.
There are no warnings/contraindications about grapefruit for these major drugs used for CRC:
5-FU, Leucovorin, Oxaliplatin, Avastin, Erbitux, and Vectibix.
For Irinotecan, from
http://www.nlm.nih.gov/medlineplus/drug ... al-dietary there is this warning:
"What special dietary instructions should I follow?
* Your doctor will tell you about a special diet to follow to help control diarrhea during your treatment. Follow these instructions carefully.
*
Talk to your doctor about eating grapefruit and drinking grapefruit juice while receiving this medicine."
(Underlining is mine).
AND, there are some PRE-meds, given at infusion for control of side-effects, especially nausea, so they might be the concern.
Two things here:
* What chemo regimen is your DM on: Folfox, Folfiri, other?
And what premeds is she receiving?
Folfiri is the regimen that has the grapefruit-cautioned Irinotecan.
* For every one of the drugs she's receiving, the clinic should have given her an Info Sheet, describing the drug, how it works, it's likely side-effects and how to control them, and foods and other drugs to avoid.
One thing to consider is that chemo nurses, angels that they are, deal with dozens of different cancer treatments every day, and often they have a mindset of 'Never do/take
xxxxxx when on chemo.'
Your parents need to confirm with the nc if there are any dietary restrictions for the medications she's receiving.
HTH, Rick