Declining WBC/ANC - post-chemo?
Posted: Mon Feb 22, 2021 3:25 pm
Hi there!
My last chemo was in early December. (Officially I'm on a chemo break - unofficially I'm ready for it to last forever.) : )
BUT today when I went in for my pump fill, they flagged me for low ANC - normal range starts at 1.5, and I was at 1.0 today.
Three weeks ago it was 1.3; three weeks before that it was 1.5. Basically it has been trending down by .2 or .3 every few weeks ever since I stopped chemo. Now it is so low that my Covid vaccine (scheduled next Thursday) is in danger!
The nurse practioner thought maybe my body had grown overly reliant on Neulasta, but I haven't had a shot of that since this summer, when we discontinued Irinotecan - so it seems like that would be quite a lag effect. In Googling, I saw a reference to RA - which I thought I might have after some positive screeners a year ago, but which we now think may have actually been paraneoplastic response. We pulled my CEA again today to see if any change - it has remained stable at ~1.1 for my last 3-4 tests, all 3-6 weeks apart.
Has anyone experienced anything similar or have any thoughts on what might be happening?
My last chemo was in early December. (Officially I'm on a chemo break - unofficially I'm ready for it to last forever.) : )
BUT today when I went in for my pump fill, they flagged me for low ANC - normal range starts at 1.5, and I was at 1.0 today.
Three weeks ago it was 1.3; three weeks before that it was 1.5. Basically it has been trending down by .2 or .3 every few weeks ever since I stopped chemo. Now it is so low that my Covid vaccine (scheduled next Thursday) is in danger!
The nurse practioner thought maybe my body had grown overly reliant on Neulasta, but I haven't had a shot of that since this summer, when we discontinued Irinotecan - so it seems like that would be quite a lag effect. In Googling, I saw a reference to RA - which I thought I might have after some positive screeners a year ago, but which we now think may have actually been paraneoplastic response. We pulled my CEA again today to see if any change - it has remained stable at ~1.1 for my last 3-4 tests, all 3-6 weeks apart.
Has anyone experienced anything similar or have any thoughts on what might be happening?