Blood work

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beach sunrise
Posts: 400
Joined: Thu Mar 05, 2020 7:14 pm

Blood work

Postby beach sunrise » Wed Jan 20, 2021 8:51 pm

Well, CEA is up 4pts in 32 days. Going to email surgeon tomorrow to push for another scan and surgery if something shows or exploratory if nothing shows.
Tomorrow will be 1yr since surgery on the primary. What luck!!!
8/19 RC CEA 82.6 T3N0M0
Neoadj 5FU/rad 6 wk
Surg 1/20 APR - margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
pre cea 24/post 5.9
FOLFOX
8 rds 6-10 CEA 11.4 4 more no oxa
7/20 CEA 11.1, 8.8
8/20 CEA 7.8
9/20 CEA 8.8, 9, 8.6
10/20 CEA 8.1
11/20 CEA 8's
12/20 CEA 8's & 9's
ADAPT+++ TM drug
MHL1+
PMS2+
MSH2+
MSH6+
POLD1 , KRAS Q61H
Chem-sens test NCI "Test failed, neo adj CR worked. Not enough ca cells to test"

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Green Tea
Posts: 340
Joined: Mon Oct 24, 2016 10:48 am

Re: Blood work

Postby Green Tea » Mon Jan 25, 2021 4:02 am

beach sunrise wrote:... Trying to get all my ducks in a row for discussion with dr on Tues about this and a few other things.

So, do you have all your ducks in a row for tomorrow's discussion with the doctor?

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beach sunrise
Posts: 400
Joined: Thu Mar 05, 2020 7:14 pm

Re: Blood work

Postby beach sunrise » Mon Jan 25, 2021 6:17 pm

Haha, yes ma'am I think I am as ready as can be unless I think of more at 2 am.
If there's anything you have thought of I should ask about let me know please. I am open to all suggestions.
8/19 RC CEA 82.6 T3N0M0
Neoadj 5FU/rad 6 wk
Surg 1/20 APR - margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
pre cea 24/post 5.9
FOLFOX
8 rds 6-10 CEA 11.4 4 more no oxa
7/20 CEA 11.1, 8.8
8/20 CEA 7.8
9/20 CEA 8.8, 9, 8.6
10/20 CEA 8.1
11/20 CEA 8's
12/20 CEA 8's & 9's
ADAPT+++ TM drug
MHL1+
PMS2+
MSH2+
MSH6+
POLD1 , KRAS Q61H
Chem-sens test NCI "Test failed, neo adj CR worked. Not enough ca cells to test"

User avatar
Green Tea
Posts: 340
Joined: Mon Oct 24, 2016 10:48 am

Re: Blood work - Elevated CEA

Postby Green Tea » Tue Jan 26, 2021 6:34 am

beach sunrise wrote:... If there's anything you have thought of I should ask about let me know please. I am open to all suggestions.

Have your doctors looked into all of the possible false positives for elevated CEA? e.g.,

    Possible false positives for elevated CEA

    Carcino Embryonic Antigen (CEA) - False Positives

    •Inflammatory Bowel Disease.
    •Pancreatitis.
    •Liver disease.
    •Tobacco use can lead to elevated CEA levels. (CEA is elevated in 19% of smokers and only 3% of the non-smoking healthy population.)
    •Diverticulitis.
    •Hepatitis.
    •Peptic ulcers.
    •Hypothyroidism.
    •Cirrhosis of the liver.
    •COPD.
    •Lung infection.
    •Pleural effusions.
    •Biliary obstruction.
    •Treatment with oral 5-FU.
    •High serum glutamic-pyruvic transaminase (sGPT) levels.

    Reference: http://www.kantrowitz.com/cancerpoints/tumormarkerfalsepositives.html

    Carcinoembryonic antigen (CEA) levels in benign gastrointestinal disease states
    Elevated circulating CEA levels occur in patients with benign gastrointestinal and hepatic disorders. These are usually less than 10 ng/ml. Of clinical importance is the influence of liver disease on the interpretation of CEA. At least 50% of patients with severe benign hepatic disease have elevated CEA levels, most often active alcoholic cirrhosis, and also chronic active and viral hepatitis, and cryptogenic and biliary cirrhosis. Patients with benign extrahepatic biliary obstruction may have increased plasma CEA, the highest in patients with co-existent cholangitis and especially liver abscess. The liver appears to be essential for the metabolism and/or excretion of CEA. Hence, liver work-up is needed to assess any patient with an elevated CEA. A damaged liver may further augment elevated CEA levels due to cancer. The increased circulating CEA observed in some patients with active ulcerative colitis tends to correlate with severity and extent of disease and usually returns to normal with remission. CEA levels also may be mildly elevated in patients with pancreatitis and in adults with colonic polyps. Smoking may contribute to the increased CEA levels seen in patients with alcoholic liver disease and pancreatitis. Therefore, in interpreting mildy elevated circulating CEA levels in patients with GI tract diseases, one must consider benign as well as malignant etiologies.
    Reference:
    https://pubmed.ncbi.nlm.nih.gov/361200/

    Have your doctors tested for and eliminated all of the above possible benign causes of elevated CEA? For example,

    • - Have you had the HCV test for viral hepatitis?
    • - Have you had any tests or tumor markers for pancreatic problems?
    • - Have your scans documented all the benign liver cysts, abscesses, hemangiomas, etc.? Are all of your liver lobes of normal size and shape?
    • - Have they tested for NAFLD (Non-alcoholic fatty liver disease)?
    • - Have they done any contrast imaging scans to check for possible anomalies or obstructions in the hepatico-biliary system?
    • - Is there any kind of hepatic angiogram that could diagnose flow problems or blockages in your liver's vascular network?
    • - Do you have any pulmonary problems that could be triggering high CEA?
    • - Have you ever been tested for possible Helicobacter Pylori infection, from a peptic ulcer?
    • - Have they checked for inflammation of the gall bladder ducts or infection of the gall bladder ?

jumpman50512
Posts: 22
Joined: Thu Jan 10, 2019 10:36 pm

Re: Blood work

Postby jumpman50512 » Mon Feb 01, 2021 9:33 pm

Hey there...

im almost in the same boat just took me a few more months and i smoke marijuana

i was at 1.5 in novemeber now jumped up to 5.6

just wondering what did you doc say?

mines isnt worried just told me to stop smoking and come back in two months

oh i also got covi twice...
Stage IV Survivor Currently (Diagnosed @ 29) currently 33
1 Met to the Liver
Colo-Rectal cancer surgery
12 rounds of chemo + Radiation + Oral Chemo
12/1/21 Colonoscopy Clean
2/1/21 CT scan Clean
2/1/21 CEA at 5.8
CEA currently at 8.8 (4/1/21)
Clean CT Scan 4/15/21

User avatar
beach sunrise
Posts: 400
Joined: Thu Mar 05, 2020 7:14 pm

Re: Blood work

Postby beach sunrise » Tue Feb 02, 2021 6:16 pm

Dr isn't concerned at this point but I am and trying to nail the source.
I wanted exploratory surgery but he won't consider it right now. Next scan is March. I know its in there somewhere and just working as hard as I can to keep it localized and not let it have a crazy shaggin wagon party with stop offs in other places to hopefully catch it early on a scan as not to miss the surgery boat.
I told my husband he might have to clear off the work bench, look at the scan, mark me and just go for it...LOL...
8/19 RC CEA 82.6 T3N0M0
Neoadj 5FU/rad 6 wk
Surg 1/20 APR - margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
pre cea 24/post 5.9
FOLFOX
8 rds 6-10 CEA 11.4 4 more no oxa
7/20 CEA 11.1, 8.8
8/20 CEA 7.8
9/20 CEA 8.8, 9, 8.6
10/20 CEA 8.1
11/20 CEA 8's
12/20 CEA 8's & 9's
ADAPT+++ TM drug
MHL1+
PMS2+
MSH2+
MSH6+
POLD1 , KRAS Q61H
Chem-sens test NCI "Test failed, neo adj CR worked. Not enough ca cells to test"


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