Anyone with a local recurrence?

Please feel free to read, share your thoughts, your stories and connect with others!
Koreysue
Posts: 197
Joined: Mon Apr 30, 2018 2:36 pm

Anyone with a local recurrence?

Postby Koreysue » Thu Nov 26, 2020 6:12 pm

Any experience with cancer returning to the colon?
At the anastomosis site or other spots in colon?
You just don’t hear of it as much as liver,lung, etc.
Wondering what all is involved treatment wise.
Ksue
Diagnosed: June 2017 stage 3 colon cancer
Sigmoid colon, 2 nodes affected
CEA at diagnosis: 6.1
Sigmoid Colectomy and folfox (chemo complete January 31, 2018)
CEA 4/2018: 2.4
CEA 7/2018: 3.7
Colonoscopy 8/2018 clean
PET scan 8/20/18 NED
CEA 11/2018: 3.8
CEA 2/2019: 3.2
CT NED 6/18/2019 / CEA : 3.4
CEA 10/21/19: 3.2
CEA 3/9/20: 3.8
CT NED /CEA 6/17/20: 3.8
CEA 11/4/20 4.6 <——— whyyyy? (will retest in a few weeks)
CT NED 12/1/20 CEA: 3.5 (happy to see a lower number)

Rock_Robster
Posts: 529
Joined: Thu Oct 25, 2018 5:27 am
Location: Melbourne, Australia

Re: Anyone with a local recurrence?

Postby Rock_Robster » Thu Nov 26, 2020 8:17 pm

It happens but definitely less common in stage IV than distant recurrence (in part because complete primary resection initially is more often possible). I believe frequency is around 5-15% depending on location, grade and treatment of initial tumour.

Treatment depends on size and location, but can be similar to the initial primary - sometimes a re-resection (aka salvage therapy) is possible; often it requires a more extensive procedure (eg APR or TPE if low recurrence). Sometimes it may be inoperable, or radiation may be used to try to treat or improve margins.
38M Australia
10/2018 Dx RC, 12cm high
Mod diff, EMVI+ LVI+. 4 liver mets
pT3N1aM1a Stage IVa. MSS NRAS G13R
CEA: Oct-18= 12; Nov-18= 14, Mar-19= 2.4, Aug-19 <2.0, Mar-20=2.2, May-20=1.9, Jun-20=2.1, Sep-20: 2.1, Dec-20: 2.3
11/18 FOLFOX x6
3/19 Liver resection
5/19 25x pelvic radiation; complete met. response
07/19 ULAR w ileo, 1/27 LN+
08/19 Found liver spot
08/19 FOLFOX x1, FOLFOXIRI x1, FOLFIRI x5
12/19 Liver resection
02/20 Ileo reversed
03/20 NED (CT/PET/MRI) - latest Dec 2020
07/20 Clear scope

Koreysue
Posts: 197
Joined: Mon Apr 30, 2018 2:36 pm

Re: Anyone with a local recurrence?

Postby Koreysue » Thu Nov 26, 2020 10:28 pm

Thank you Rock Lobster
I was just not finding much info, and because I have symptoms that are concerning me, I want to have some idea of what I’m looking at.
Ksue
Diagnosed: June 2017 stage 3 colon cancer
Sigmoid colon, 2 nodes affected
CEA at diagnosis: 6.1
Sigmoid Colectomy and folfox (chemo complete January 31, 2018)
CEA 4/2018: 2.4
CEA 7/2018: 3.7
Colonoscopy 8/2018 clean
PET scan 8/20/18 NED
CEA 11/2018: 3.8
CEA 2/2019: 3.2
CT NED 6/18/2019 / CEA : 3.4
CEA 10/21/19: 3.2
CEA 3/9/20: 3.8
CT NED /CEA 6/17/20: 3.8
CEA 11/4/20 4.6 <——— whyyyy? (will retest in a few weeks)
CT NED 12/1/20 CEA: 3.5 (happy to see a lower number)

Rock_Robster
Posts: 529
Joined: Thu Oct 25, 2018 5:27 am
Location: Melbourne, Australia

Re: Anyone with a local recurrence?

Postby Rock_Robster » Fri Nov 27, 2020 2:26 am

Koreysue wrote:Thank you Rock Lobster
I was just not finding much info, and because I have symptoms that are concerning me, I want to have some idea of what I’m looking at.
Ksue

No worries; given you’ve had surgery and chemo I’m sure there’s plenty of more benign reasons for your symptoms, but good to be cautious about these things! Best of luck
38M Australia
10/2018 Dx RC, 12cm high
Mod diff, EMVI+ LVI+. 4 liver mets
pT3N1aM1a Stage IVa. MSS NRAS G13R
CEA: Oct-18= 12; Nov-18= 14, Mar-19= 2.4, Aug-19 <2.0, Mar-20=2.2, May-20=1.9, Jun-20=2.1, Sep-20: 2.1, Dec-20: 2.3
11/18 FOLFOX x6
3/19 Liver resection
5/19 25x pelvic radiation; complete met. response
07/19 ULAR w ileo, 1/27 LN+
08/19 Found liver spot
08/19 FOLFOX x1, FOLFOXIRI x1, FOLFIRI x5
12/19 Liver resection
02/20 Ileo reversed
03/20 NED (CT/PET/MRI) - latest Dec 2020
07/20 Clear scope

Nicolouna
Posts: 39
Joined: Fri Nov 08, 2013 6:30 pm

Re: Anyone with a local recurrence?

Postby Nicolouna » Fri Nov 27, 2020 11:19 am

So I have a pretty long and complicated history with colon cancer (will update my signature shortly), but basically 7 years after my primary diagnosis, colitis was seen in a follow-up CT scan. I did not have any symptoms or discomfort. I went for PET scan, which showed nothing. I was due for my routine colonoscopy in a few months but it was bumped up. A small area of superficial redness was found 10cm away from the anastomosis, no mass per se and no colitis. A biopsy was obviously taken and low and behold, invasive adenocarcinoma. I was fast tracked for a partial colectomy surgery. The transverse colon was resected and the pathology showed a 1.2 cm tumor, 0/20 nodes and clear surgical margins... "in theory" Stage 2b or 2c. They consider this to be a new primary colon cancer, therefore local recurrence. After much debate, it was recommended for me to have adjuvant chemo, Folfox or Xelox... I opted for Xelox, as per my onco, the stats could be 1-2% more favorable but truth be told, the stats don't really apply to me. So what "sold" me was less hospital visits (8 infusions versus 12) and no 48h 5-FU, which I totally despised when I had FOLFOX and FOLFIRI. I just had my first infusion and taking my Xeloda at home... 1 down, 7 to go...
Dx @ 27yo, female w colon cancer (T4N0M0)
Aug 2013: Right hemicolectomy
FOLFOX: Oct 2013-April 2014, NED
May 2016: had a baby ❤️
June 2017: L ovarian met, surgical removal
July 2017: ?met to pancreas
Aug 2017: FOLFIRI
Dec 2017: Whipple’s. 1/36 nodes+
May 2018: 12 FOLFIRI done, NED
Sept 2018: abnormal cyst R ovary - surgical removal, no cancer (false alarm)
Dec 2019: abdo wall met, resected, clear margins, no further treatment
Oct 2020: new primary colon ca (T4N0), partial colectomy
Nov 2020: XELOX started

User avatar
Green Tea
Posts: 290
Joined: Mon Oct 24, 2016 10:48 am
Location: Nusa Tenggara

Re: Anyone with a local recurrence?

Postby Green Tea » Fri Nov 27, 2020 11:43 am

Koreysue wrote:... I was just not finding much info...

Have you looked into the procedure called "Complete Mesocolic Excision"? I think this might be something like the "complete primary resection" that Rock_Robster was referring to.

In any event, I don't think you would have much to worry about in terms of local recurrence if your surgeon in fact did a "complete primary resection" with clear margins (proximal, distal, and circumferential/radial).

What kind of surgery did you have, open or laparoscopic?

https://link.springer.com/article/10.1007/s10353-020-00677-6

prayingforccr
Posts: 70
Joined: Sun Jun 28, 2020 4:44 pm

Re: Anyone with a local recurrence?

Postby prayingforccr » Fri Nov 27, 2020 1:11 pm

My rectal tumor had a complete response after chemoradiation/trial drug/FOLFOX as confirmed by two biopsies a month a part.

However, they spotted something on my mri which may be tumor deposits in the pelvis.

I am terrified and will be biopsied this Monday.

I’m praying what they see is inflammation or tumor debris as the deposits (which are matastes) would have to have formed during FOLFOX chemotherapy or within the month between the end of treatment and now.
Nov 2019: colonoscopy
Dec 2019: diagnosed with stage 3 rectal cancer 6+cm tumor
Jan-mar 2020: 20 sessions of radiation, mon-fri capecetibine, mon-fri clinical trial drug m3814
Apr 2020: sigmoidosvopy confirmed tumor/scar 3.7cm with significant tumor necrosis but some persistent disease
July 2020: began 8 treatmentsFOLFOX
August 2020: ct scan reveals scarbed reduced to 2.7cm CEA is 1.5
Nov 2020: Primary tumor had complete response. Possible tumor deposits on latest mri. Biopsy negative for cancer.

Koreysue
Posts: 197
Joined: Mon Apr 30, 2018 2:36 pm

Re: Anyone with a local recurrence?

Postby Koreysue » Fri Nov 27, 2020 3:01 pm

Green Tea wrote:
Koreysue wrote:... I was just not finding much info...

Have you looked into the procedure called "Complete Mesocolic Excision"? I think this might be something like the "complete primary resection" that Rock_Robster was referring to.

In any event, I don't think you would have much to worry about in terms of local recurrence if your surgeon in fact did a "complete primary resection" with clear margins (proximal, distal, and circumferential/radial).

What kind of surgery did you have, open or laparoscopic?

https://link.springer.com/article/10.1007/s10353-020-00677-6


Green Tea,
I had laparoscopic sigmoid colectomy with clean margins. Really hoping for benign causes for this bleeding. I have a ct on Monday with results Tuesday at 4
Ksue
Diagnosed: June 2017 stage 3 colon cancer
Sigmoid colon, 2 nodes affected
CEA at diagnosis: 6.1
Sigmoid Colectomy and folfox (chemo complete January 31, 2018)
CEA 4/2018: 2.4
CEA 7/2018: 3.7
Colonoscopy 8/2018 clean
PET scan 8/20/18 NED
CEA 11/2018: 3.8
CEA 2/2019: 3.2
CT NED 6/18/2019 / CEA : 3.4
CEA 10/21/19: 3.2
CEA 3/9/20: 3.8
CT NED /CEA 6/17/20: 3.8
CEA 11/4/20 4.6 <——— whyyyy? (will retest in a few weeks)
CT NED 12/1/20 CEA: 3.5 (happy to see a lower number)

Koreysue
Posts: 197
Joined: Mon Apr 30, 2018 2:36 pm

Re: Anyone with a local recurrence?

Postby Koreysue » Fri Nov 27, 2020 3:02 pm

prayingforccr wrote:My rectal tumor had a complete response after chemoradiation/trial drug/FOLFOX as confirmed by two biopsies a month a part.

However, they spotted something on my mri which may be tumor deposits in the pelvis.

I am terrified and will be biopsied this Monday.

I’m praying what they see is inflammation or tumor debris as the deposits (which are matastes) would have to have formed during FOLFOX chemotherapy or within the month between the end of treatment and now.


I know that terror feeling well. Hoping the best for you.
Ksue
Diagnosed: June 2017 stage 3 colon cancer
Sigmoid colon, 2 nodes affected
CEA at diagnosis: 6.1
Sigmoid Colectomy and folfox (chemo complete January 31, 2018)
CEA 4/2018: 2.4
CEA 7/2018: 3.7
Colonoscopy 8/2018 clean
PET scan 8/20/18 NED
CEA 11/2018: 3.8
CEA 2/2019: 3.2
CT NED 6/18/2019 / CEA : 3.4
CEA 10/21/19: 3.2
CEA 3/9/20: 3.8
CT NED /CEA 6/17/20: 3.8
CEA 11/4/20 4.6 <——— whyyyy? (will retest in a few weeks)
CT NED 12/1/20 CEA: 3.5 (happy to see a lower number)

Koreysue
Posts: 197
Joined: Mon Apr 30, 2018 2:36 pm

Re: Anyone with a local recurrence?

Postby Koreysue » Fri Nov 27, 2020 3:06 pm

Nicolouna wrote:So I have a pretty long and complicated history with colon cancer (will update my signature shortly), but basically 7 years after my primary diagnosis, colitis was seen in a follow-up CT scan. I did not have any symptoms or discomfort. I went for PET scan, which showed nothing. I was due for my routine colonoscopy in a few months but it was bumped up. A small area of superficial redness was found 10cm away from the anastomosis, no mass per se and no colitis. A biopsy was obviously taken and low and behold, invasive adenocarcinoma. I was fast tracked for a partial colectomy surgery. The transverse colon was resected and the pathology showed a 1.2 cm tumor, 0/20 nodes and clear surgical margins... "in theory" Stage 2b or 2c. They consider this to be a new primary colon cancer, therefore local recurrence. After much debate, it was recommended for me to have adjuvant chemo, Folfox or Xelox... I opted for Xelox, as per my onco, the stats could be 1-2% more favorable but truth be told, the stats don't really apply to me. So what "sold" me was less hospital visits (8 infusions versus 12) and no 48h 5-FU, which I totally despised when I had FOLFOX and FOLFIRI. I just had my first infusion and taking my Xeloda at home... 1 down, 7 to go...


So am I understanding correctly that you have had 2 colectomies? Or only the colectomy after the 2nd occurrence?
Ksue
Diagnosed: June 2017 stage 3 colon cancer
Sigmoid colon, 2 nodes affected
CEA at diagnosis: 6.1
Sigmoid Colectomy and folfox (chemo complete January 31, 2018)
CEA 4/2018: 2.4
CEA 7/2018: 3.7
Colonoscopy 8/2018 clean
PET scan 8/20/18 NED
CEA 11/2018: 3.8
CEA 2/2019: 3.2
CT NED 6/18/2019 / CEA : 3.4
CEA 10/21/19: 3.2
CEA 3/9/20: 3.8
CT NED /CEA 6/17/20: 3.8
CEA 11/4/20 4.6 <——— whyyyy? (will retest in a few weeks)
CT NED 12/1/20 CEA: 3.5 (happy to see a lower number)

Dennyp
Posts: 6
Joined: Thu Oct 29, 2020 9:28 pm

Re: Anyone with a local recurrence?

Postby Dennyp » Sat Jan 09, 2021 12:10 am

I have a recurrence to a single common iliac lymph node which is being treated as a local recurrence. I had 5 rounds of FOFIRI w.hich shrunk the lymph node and will have surgery next Friday to remove the lymph node.


Return to “Colon Talk - Colon cancer (colorectal cancer) support forum”



Who is online

Users browsing this forum: No registered users and 5 guests