Rachel, thank you for your response. It gives me a lot of hope. I'm curious how many mets you had? For me, i dont think it is as much the size of the mets, although i have 3 large ones that have shrunk quite a bit - the issue is all the small ones and their location. The large ones were 5.3 x 4.6, 5.5 x 4.8 and 5.2 x 4.6. they are now 0.9 x 0.7, 1.5 x 1.4 and 3.2 x 2.5. Not really sure how many small ones there were, but there are about 20 now; my sense is there were maybe 30 to start. They are all smaller and he said some could actually not be alive anymore, but he wouldn't know until he went in.
Anyway, I am actually getting my infusion as we speak, but my Dr opted to go with a long infusion of FOLFOX as he thinks it could still be effective in containing the tumors (and doesnt see a path to surgery), and i think he wants to save FOLFIRI for later.
This is why i am looking for hope that maybe the FOLFIRI cold work. If i have to wait thru a few more FOLFOX treatments, that is fine.
Dx 9/2019 CC Stage IV
Annular sigmoid neoplasm in the distal sigmoid
3 met in liver ~5cm, 20+ small mets
Baseline CEA: 266
1 lymph node outside liver
9/2019: start FOLFOX
2/2020: resect colon; HAI pump implanted; lymph node removed
5/2020: 5 FUDR via HAI pump
7/2020: 3 liver met ~2cm x 1cm
7/2020: CEA 9;,remove oxyplatin due to allergic reaction
9/2020: CEA creeps up to 15
9/2020: 19 FOLFOX w/oxyplatin; 4 FOLOX w/o oxyplatin due to reaction
10/2020: Restarted 24th FOLFOX w/oxyplatin slow infusion