Tumor Surgery and CEA

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Joined: Tue Mar 28, 2017 5:32 pm

Tumor Surgery and CEA

Postby sdino » Wed Oct 07, 2020 11:41 am

Quick question, my Wife had a sizable 5cm tumor removed from her left lung. She still has two 2cm tumors in her right lung. Would her CEA go down because of less tumor burden after resection ? Or because CEA is bloodborne, would there not be change in CEA ?
Caregiver for Wife 54 yrs old
DX:11/16-CC sigmoid colon
Lung Mets: 25+ Bilateral ranging 4mm-5.0cm
iTCR TIL Trial NCT03412877 4/19 to 7/19 Off trial, - Sept. 2019 TIL trial NCT01174121
CT Scans: 7/2020 lung met shrinkage 36%, 3 lung mets left, two Liver mets destroyed by TILs
Brain tumor removal 3/2020
CEA:16-11/16; 5 -9/18; 63 -8/19; 1 -1/20; 0.8-5/20

Posts: 438
Joined: Tue Mar 12, 2019 2:41 pm
Location: Montana

Re: Tumor Surgery and CEA

Postby Claudine » Thu Oct 08, 2020 10:09 am

My husband's CEA dropped both after his adrenalectomy in February, then after his partial corpectomy in May, so I think that decreasing tumor burden could lessen its value.
Wife of Dx 04/18 (51 yo). MSS, KRAS G12A
No primary (involuted?)
Lytic tumor L4 vertebrae, EBRT 04/18, SBRT 02/19
Resect small intestine 05/18 (no cancer - Crohn's)
Failed adjuvant Xelox
Folfiri + Avastin 03/19 to 01/20
6.7 cm left adrenal mass 03/19, successful resection 02/20
CEA since 03/19: high 58, low 3.2, now 24.1
Scan 03/19: Multiple small lung nodules, now gone
PET 04/20 uptake by L4
L3-L4-L5 fusion surgery and partial corpectomy 05/20
Scan 09/20: nothing to report

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