CEA and bloodwork

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beach sunrise
Posts: 216
Joined: Thu Mar 05, 2020 7:14 pm

CEA and bloodwork

Postby beach sunrise » Thu Sep 03, 2020 3:07 am

Hi you guys, onc called to go over bloodwork. He said all is perfect but CEA is up to 8.8. He wanted to stop xeloda until we do a PET scan. I said NO to stopping xeloda for 3-4 weeks. So, continuing with it until scan and see if anything is going on or not. My concerns are why did cea rise but everything else look good? Could it be that I had to slack off PSK until more arrived and some other supplements? Idk. Here are some markers and hopefully you all can help me see something onc and myself are missing maybe.
hgb 12.9 g/dL mch 35% pg mcv 103.4fl platelets 166 (down from 229) rbc 3.54 wbc 7.3 mpv 10.6fl rdw-sd 65.5fl rdw-cv 18%

neutrophils 5.98 lymphocytes .42 10^3/ul neutrophils 82.2% lymphocytes 5.5% (down from 9%) chloride 109 alp 97 (up from 86) alt 14 ast 23

billi total .70 (up from .6) albumin 3.8 cea 8.8 (up 1 pt)
8/19 RC CEA 86 T3N0M0
Neoadj 5FU/rad 6 wk
Surg 1-21-20 APR - margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
pre cea 24/post 5.9
mFOLFOX6 CEA 7
8 rds 6-10 CEA 11.4 4 more no oxa
6-17 CEA 11.1
7-2 CEA 11.1
7-16 CEA 10.3
7-28 CEA 8.8
8-11 CEA 7.8
9-1 CEA 8.8
9-8 CEA 9
9-16 CEA 9
MHL1+
PMS2+
MSH2+
MSH6+
POLD1
Chem-sens test NCI "Test failed, neo adj CR worked. Not enough ca cells to test"

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CRguy
Posts: 10230
Joined: Sun Feb 10, 2008 6:00 pm

Re: CEA and bloodwork

Postby CRguy » Thu Sep 03, 2020 10:46 pm

just some thoughts here :

CEA can increase for a WHOLE shitload of reasons NOT related to CRC !
CEA can increase when the chemo IS WORKING and the tumors are dying !
CEA levels can be subject to lab errors so maybe a redo is in order ?

Whenever my docs and I got an "unexpected" result on ANY test ...
a recheck of that test was the first step to follow up.

OH and BTW ....
when posting lab result values, it is always a good idea to also include the lab NORMAL ranges for your own lab reports
While increases and decreases are of value, there are many different reporting and measuring criteria out there,
so to give relevant feedback it is necessary to know the Lab Normal frame of reference.

Cheers and best wishes
CRguy
Caregiver x 4
Stage IV A rectal cancer/lung met
13 Year survivor
my life is an ongoing totally randomized UNcontrolled experiment with N=1 !
Review of my Journey so far

kandj
Posts: 298
Joined: Sun Sep 27, 2015 11:29 am

Re: CEA and bloodwork

Postby kandj » Thu Sep 03, 2020 11:35 pm

My husbands CEA was less than .5 when he was diagnosed, and his liver was riddled with mets. The highest it ever was was 10.5 and that was when there were no active tumors and he was on chemo, but nearing the end of a 6 month cycle.
wife to DH, dx 8/15 stage IV @36, numerous unresectable liver Mets
resection and HAI placed 12/15
Liver resection 5/19/2016 15-20 mets removed (surgeon lost count, but it hopeful he got it all!)
Recurrence 7/2017 4 Liver mets and one possible lung met
Radiation on liver Mets 12/17
Lung met 10/18
VATS on lung met 11/18 started xeloda
Chemo break 6/19-11/19 lung/adrenal gland recurrence 11/19
Adrenal ablation2/20 Robotic Assisted VATS 3/20 Xeloda again

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beach sunrise
Posts: 216
Joined: Thu Mar 05, 2020 7:14 pm

Re: CEA and bloodwork

Postby beach sunrise » Fri Sep 04, 2020 1:36 am

Thanks CRguy for the tip on including normal lab values! And the other thoughts.
KandJ, thank you for sharing your experience with cea rises.

I am very worried for sure. I wish PET could be tomorrow :)
PET scheduled for 9-25-20!
8/19 RC CEA 86 T3N0M0
Neoadj 5FU/rad 6 wk
Surg 1-21-20 APR - margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
pre cea 24/post 5.9
mFOLFOX6 CEA 7
8 rds 6-10 CEA 11.4 4 more no oxa
6-17 CEA 11.1
7-2 CEA 11.1
7-16 CEA 10.3
7-28 CEA 8.8
8-11 CEA 7.8
9-1 CEA 8.8
9-8 CEA 9
9-16 CEA 9
MHL1+
PMS2+
MSH2+
MSH6+
POLD1
Chem-sens test NCI "Test failed, neo adj CR worked. Not enough ca cells to test"

michelle c
Posts: 1906
Joined: Wed Dec 02, 2009 3:58 am

Re: CEA and bloodwork

Postby michelle c » Fri Sep 04, 2020 7:48 pm

I see that it was 8.8 the time before that too, and it’s been as high as 11.4. Just wondering if it’s normal for yours to fluctuate. It’s normal for CEA to fluctuate somewhat, and very unlikely to ever be the same.
25 May 09 Dx with CC (sigmoid colon) 2 days after my 44th b'day
CEA prior to surgery 4.7
3 Jun 09 LAR - Stage III 3/10 lymph nodes
6 Jul - 10 Dec 09 12 cycles FOLFIRI
Genetic testing - inconclusive for Lynch
Jul 12 port removed & hernia repair


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