I recevied a piece of good news in my first post-surgery report
- Clean margins with closest margin over five inches away from the tumor (the removed 20 inches of colon, apparently)
- No infiltration in spleen (which was removed as part of surgery)
- Out of 37 lymphatic nodes removed none of them showed metastasis!
This puts my disease for now in the T3N0 staging
They will tell me next week whether chemotherapy is required or not.
It is true that I have two milimetric "ground glass" dots in my right lung´s median lobe but my doctor reassured me that it was very unlikely to be metastasis, sice aparently liver metastatis occurs almost invariably before lung metastasis does and my liver appears to be clean.
Another point is that my protein MSH6 is non expressed while the other three MMR proteins MLH1, MSH2 and PMS2 are conserved.
This was a bit of a surprise since deficient-MMR tumors are most common on the right side of the colon, while mine was found in the left side (near the spleen).
Does the loss of MSH6 indicate likelyhood of Lynch Syndrome, should I get genetic testing for the sake of my family?
Does this make me a candidate to Inmunotherapy as first line treatment?
Please, wise people of the forum, let me know what to make of this.
Thank you, love and health