LVI positive/neg

Please feel free to read, share your thoughts, your stories and connect with others!
User avatar
beach sunrise
Posts: 118
Joined: Thu Mar 05, 2020 7:14 pm

LVI positive/neg

Postby beach sunrise » Mon Jun 29, 2020 12:07 pm

Hi everyone, Question: Is LVI always present if you have lymph node involvement? Why or why not?
Dx 8/19, RC, CEA 86, clinical T3N0M0
Neoadj 5FU/rad 6 wks
Surg 1-21-20 APR ostomy, neg margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
presurg cea 24/post 5.9
Adj mFOLFOX6, cea 7
8 rds 6-10 CEA 11.4, 4 more no oxa
6-17: CEA 11.1 AFP 11.2 CA125 25.7 CA199 9
7-2: CEA 11.1 AFP 5.3 CA125 24.8 CA199 8
MHL1+
PMS2+
MSH2+
MSH6+
Chemo sensitivity test NCI "Test failed, neo-adj chemorad did its job. Not enough ca. cells to test."

BLZ85
Posts: 6
Joined: Thu Mar 12, 2020 4:52 pm

Re: LVI positive/neg

Postby BLZ85 » Tue Jun 30, 2020 9:36 am

Hello!

My pathology (I did 4 rounds of FOLFOX and 6 weeks of chemo/radiation prior to surgery) was LVI negative but I had some viable cells in 1 node. I am not sure if it was negative because of prior treatment or if it was always negative. But I did have lymph node involvement. I’m sorry if that doesn’t really answer your question.
34yo Female Dx 2/27/2019
T3N2M0 upper rectum
MSS/pMMR
4 rounds of FOLFOX6
Radiation/xeloda completed 8/8/19
LAR 10/22/19, no residual tumor or cells in rectum
1 positive node after chemo/radiation
No bag
3 rounds of CAPOX
Clear scan 1-16-20
Clear colonoscopy 3-4-20
CEA 1.5 2-28-20, 1.4 5-28-20
Clear scan 7-1-20
Currently NED

User avatar
beach sunrise
Posts: 118
Joined: Thu Mar 05, 2020 7:14 pm

Re: LVI positive/neg

Postby beach sunrise » Wed Jul 01, 2020 2:33 am

thank you so much for your input. It helps! I've been researching this and seems its a crap shoot I guess.
Dx 8/19, RC, CEA 86, clinical T3N0M0
Neoadj 5FU/rad 6 wks
Surg 1-21-20 APR ostomy, neg margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
presurg cea 24/post 5.9
Adj mFOLFOX6, cea 7
8 rds 6-10 CEA 11.4, 4 more no oxa
6-17: CEA 11.1 AFP 11.2 CA125 25.7 CA199 9
7-2: CEA 11.1 AFP 5.3 CA125 24.8 CA199 8
MHL1+
PMS2+
MSH2+
MSH6+
Chemo sensitivity test NCI "Test failed, neo-adj chemorad did its job. Not enough ca. cells to test."

Beckster
Posts: 417
Joined: Thu Jan 12, 2017 3:01 pm
Location: New Jersey

Re: LVI positive/neg

Postby Beckster » Thu Jul 02, 2020 3:53 pm

I had LVI with no lymph node involvement. Stage 2A T3N0M0. LVI is considered a high risk of recurrence, but it is subjective. I have been cancer free for almost 4 years.
57/F
DX:(CC) 10/19/16
11/4/16- Lap right hemi(cecum)
CEA- Pre Op (1.9), Pre Chemo (2.5)
Type: Adenocarcinoma
Tumor size:3.5 cm x 2.5 x 0.7 cm
Grade: G3 (path) G2 (pre-op)
TNM: T3N0M0/IIA
LN: 0/24
LVI present
Surgical margins: clear
MSS
12/27/2016 - Capeox, anaphylactic reaction
1/2/17 to 6/9/17- Xeloda monotherapy
6/17,12/17,6/18,12/18, 6/19, 12/19 CT Scan NED :D
CEA- 6/17- 3.6, 9/17- 2.8 12/17-2.8, 3/18-3.1, 6/18-3.0, 9/18 2.8, 12/18 2.5 3/19 3.1 6/19 3.1 9/19 2.6 12/19 2.8 6/20 3.0
Clear Colonoscopy 10/17, 11/19 :D

User avatar
beach sunrise
Posts: 118
Joined: Thu Mar 05, 2020 7:14 pm

Re: LVI positive/neg

Postby beach sunrise » Tue Jul 07, 2020 10:54 am

Thank you, Beckster! I guess this is just something that will drive you crazy trying to understand. I hope you are doing good!
Dx 8/19, RC, CEA 86, clinical T3N0M0
Neoadj 5FU/rad 6 wks
Surg 1-21-20 APR ostomy, neg margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
presurg cea 24/post 5.9
Adj mFOLFOX6, cea 7
8 rds 6-10 CEA 11.4, 4 more no oxa
6-17: CEA 11.1 AFP 11.2 CA125 25.7 CA199 9
7-2: CEA 11.1 AFP 5.3 CA125 24.8 CA199 8
MHL1+
PMS2+
MSH2+
MSH6+
Chemo sensitivity test NCI "Test failed, neo-adj chemorad did its job. Not enough ca. cells to test."


Return to “Colon Talk - Colon cancer (colorectal cancer) support forum”



Who is online

Users browsing this forum: No registered users and 32 guests