An aspirin a day helps keep bowel cancer away

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del
Posts: 118
Joined: Thu Mar 03, 2016 11:21 pm
Location: Sydney, Australia

An aspirin a day helps keep bowel cancer away

Postby del » Sun Jun 14, 2020 11:26 pm

Encouraging new study about aspirin that was published in The Lancet (probably the top medical journal in the world).

An aspirin a day helps keep bowel cancer away, study finds
https://www.smh.com.au/national/an-aspi ... 5524r.html
Male, 33 @ dx, stage 1 RC (T1N0M0 0/29 LNs)
2016-02 - Cancerous polyp removed during colonscopy, 0.5 mm margin
2016-03 - ULAR & TME surgery, temp ileostomy
2016-04 - DVT, pulmonary embolism
2016-11 - Ileostomy reversal
2018-10 - Another DVT & PE

Claudine
Posts: 386
Joined: Tue Mar 12, 2019 2:41 pm
Location: Montana

Re: An aspirin a day helps keep bowel cancer away

Postby Claudine » Mon Jun 15, 2020 12:43 pm

DH is about to start taking aspirin in combination with acetaminophen for sciatica-like pain control; if it can also prevent recurrence then that's a major bonus!
Wife of Dx 04/18 (51 yo). MSS, KRAS G12A
No primary (involuted?)
Lytic tumor L4 vertebrae, EBRT 04/18, SBRT 02/19
Resect small intestine 05/18 (no cancer - Crohn's)
Failed adjuvant Xelox
Folfiri + Avastin 03/19 to 01/20
6.7 cm left adrenal mass 03/19, successful resection 02/20
CEA since 03/19: high 58, low 3.2, now 4.4
Scan 03/19: Multiple small lung nodules up to 5mm
Scan 12/19: one 1mm stable nodule
PET 04/20 uptake by L4
L3-L4-L5 fusion surgery and residual tumor removal 05/20

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henry123
Posts: 212
Joined: Sun Oct 08, 2017 3:25 am

Re: An aspirin a day helps keep bowel cancer away

Postby henry123 » Wed Jun 17, 2020 12:39 am

I have been taking aspirin 150 mg since the past 3 years or so.
It is definitely beneficial for people having Lynch Syndrome as per the various articles I have read.
I would strongly recommend it.
46yo M msi-high Lynch +ve
5/16 lap AR 14/21 L nodes +ve
T4N2M1
7/16 Capox 9 cyc
9/16 cea 2
1/17 550
PET CT mets in lung & peri
iri+ avast fail
3/17 10577
4/17 regro fail
5/17 cea 28800
5/17 CT inc in size of mes nodes ,onset of multi nodules in liver
6/17 Opdivo start
7/17 26754
8/17 5623
9/17 497
10/17 52
11/17 12
CT all clear exc a nodule in Lung. liver norm
1/18 3.6
4/18 2
Aspirin start
6/18 1.5 CT clear
12/18 1.1 NED
6/19 .9 CT clear
1/20 NED Opdivo stop

Koreysue
Posts: 153
Joined: Mon Apr 30, 2018 2:36 pm

Re: An aspirin a day helps keep bowel cancer away

Postby Koreysue » Wed Jun 17, 2020 8:11 pm

That’s really promising. Thanks for sharing :D
Ksue
Diagnosed: June 2017 stage 3 colon cancer
Sigmoid colon, 2 nodes affected
CEA at diagnosis: 6
Sigmoid Colectomy and folfox (chemo complete January 31, 2018)
CEA 4/2018: 2.4
CEA 7/2018: 3.7
Colonoscopy 8/2018 clean
PET scan 8/20/18 NED (cea rise a mystery for now, doc said maybe all the smoke in my town from forest fires)
CEA 11/2018: 3.8
CEA 2/2019: 3.2
CT NED 6/18/2019 / CEA : 3.4
CEA 10/21/19: 3.2
CEA 3/9/20: 3.8
CT NED /CEA 6/17/20: 3.8

Gravelyguy
Posts: 309
Joined: Thu Jul 05, 2018 6:03 pm

Re: An aspirin a day helps keep bowel cancer away

Postby Gravelyguy » Wed Jun 17, 2020 8:48 pm

I had my 6 month scans and visit today at Mayo. I have been taking a low dose aspirin for over a year now and asked my onc. what the recommended dosage was as I tend to bleed pretty easily. He told me to keep taking what I am, but there isn’t a definitive dosage at this time.

Dave
6/17 dx mRC t3n1m1 very low rectal tumor 2 liver Mets 1.3 cm and .9 cm

6/17 begin 4 rounds Folfox w/Vectibix
9/17 short course radiation
10/17 rectal and liver resection LAR with coloanal anastomosis (no rectum left)
11/17-3/18 8 rounds Folfox
6/18 still NED!! Takedown
8/28/18 still NED! CEA .8 new low for me
10/18/18 colonoscopy clear
12/12/18 clear scans, CEA .9 still NED!
6/11/19 clear scans CEA 1.0
12/19/19 clear scans CEA 1.0 still NED!
6/17/20 clear scans CEA 1.1 still NED!

del
Posts: 118
Joined: Thu Mar 03, 2016 11:21 pm
Location: Sydney, Australia

Re: An aspirin a day helps keep bowel cancer away

Postby del » Thu Jun 18, 2020 6:51 pm

I'm surprised more bowel cancer patients aren't prescribed daily aspirin. I have read about other studies which have shown aspirin reduces your risk for stroke and heart attack too. Unfortunately I'm on anticoagulants for life, so I am not able to take aspirin (too much of a bleeding risk).
Male, 33 @ dx, stage 1 RC (T1N0M0 0/29 LNs)
2016-02 - Cancerous polyp removed during colonscopy, 0.5 mm margin
2016-03 - ULAR & TME surgery, temp ileostomy
2016-04 - DVT, pulmonary embolism
2016-11 - Ileostomy reversal
2018-10 - Another DVT & PE

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CRguy
Posts: 10179
Joined: Sun Feb 10, 2008 6:00 pm

Re: An aspirin a day helps keep bowel cancer away

Postby CRguy » Thu Jun 18, 2020 7:26 pm

For the record I do take daily ASA / aspirin (85 mg) for the cardiovascular benefits, since before diagnosis
BUTT ... still ended up with Stage IV CRC !!!!! :twisted:
So I guess I would not be in the 50% who benefit for CRC preventives :shock:

Having said that, I would / do continue to take it and also would like some more info from better defined studies as to dosages.
85 mg up to 600 mg is a HUGE variation in doses and while the 85 mg really does not affect my clotting factors,
I am sure 600 mg daily would absolutely have an impact of prolonged bleeding times.

It is not always the case that :
" if more is better ... TOO MUCH is just right ! "

Cheers all
CRguy
Caregiver x 4
Stage IV A rectal cancer/lung met
13 Year survivor
my life is an ongoing totally randomized UNcontrolled experiment with N=1 !
Review of my Journey so far

I_will_fight
Posts: 11
Joined: Mon Jun 29, 2020 3:38 pm

Re: An aspirin a day helps keep bowel cancer away

Postby I_will_fight » Sun Jul 05, 2020 1:40 pm

I have bi-lateral tinnitus (now it seems kind of silly that this used to worry me, funny how Cancer changes our perspective).

Is it not the case that Aspirin can trigger (or worsen) tinnitus? I know it seems like a good trade off but Tinnitus can be really annoying.

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CRguy
Posts: 10179
Joined: Sun Feb 10, 2008 6:00 pm

Re: An aspirin a day helps keep bowel cancer away

Postby CRguy » Sun Jul 05, 2020 5:48 pm

No it is not really annoying homie...
it is MEGA EFFING !!!!!!!! ANNOYING :twisted: been there and am doing that as well

True story : my original family Doc once told me that is how they judged the proper DOSE of ASA in the bad old days.
increase the dose until the tinnitus is too bad ... and THEN reduce it :shock: :roll:
Seriously !

I hear you my friend
"what ... is that the phone ?
It's for you "
:mrgreen:

Cheers and best wishes
keep on keepin' ON
CRguy
Caregiver x 4
Stage IV A rectal cancer/lung met
13 Year survivor
my life is an ongoing totally randomized UNcontrolled experiment with N=1 !
Review of my Journey so far

I_will_fight
Posts: 11
Joined: Mon Jun 29, 2020 3:38 pm

Re: An aspirin a day helps keep bowel cancer away

Postby I_will_fight » Mon Jul 06, 2020 1:07 am

CRguy wrote:No it is not really annoying homie...
it is MEGA EFFING !!!!!!!! ANNOYING :twisted: been there and am doing that as well

True story : my original family Doc once told me that is how they judged the proper DOSE of ASA in the bad old days.
increase the dose until the tinnitus is too bad ... and THEN reduce it :shock: :roll:
Seriously !

I hear you my friend
"what ... is that the phone ?
It's for you "
:mrgreen:

Cheers and best wishes
keep on keepin' ON
CRguy


Oh man, sorry to hear that your T is so unbeareble, my T is not so bad, I am normally able to forget about it during daytime activities. it is always there but it does not always bother me.

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CRguy
Posts: 10179
Joined: Sun Feb 10, 2008 6:00 pm

Re: An aspirin a day helps keep bowel cancer away

Postby CRguy » Mon Jul 06, 2020 12:01 pm

Like so much of this CRC nonsense ... it is bearable and does change thru the day,
depending upon ambient background noise and activity.

I understand there are noise cancelling hearing aids which may help with this.

My problem : my hearing acuity is better than my younger wife's,
so I am not ready for ear buds !!!

Can't win sometimes

Cheers
CRguy
Caregiver x 4
Stage IV A rectal cancer/lung met
13 Year survivor
my life is an ongoing totally randomized UNcontrolled experiment with N=1 !
Review of my Journey so far


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