CEA rising

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Sam Phillips
Posts: 3
Joined: Wed Jun 10, 2020 8:32 am
Facebook Username: Sam Phillips

CEA rising

Postby Sam Phillips » Wed Jun 10, 2020 8:41 am

Hi I am new here I have stage 4 with 2 lung mets I have been doing avastin and Xeolda since reacurrance I have noticed since starting my CEA keeps rising over the 8 months it started at 1.4 now at 4.9 my last scan 2 months ago showed they are scar tissue has this happened to anyone else I am worried it is spreading anyone had constant rise and be nothing Thankyou

stu
Posts: 1355
Joined: Sat Aug 17, 2013 5:46 pm

Re: CEA rising

Postby stu » Wed Jun 10, 2020 4:00 pm

Happened to my mum both times she was on chemo . Caused by the chemo itself . Her CEA was always low but did rise each time . It was an anxious time but each year her scans showed significant shrinkage.
Take care ,
Stu
supporter to my mum who lives a great life despite a difficult diagnosis
stage4 2009 significant spread to liver
2010 colon /liver resection
chemo following recurrence
73% of liver removed
enjoying life treatment free
2016 lung resection
Oct 2017 nice clear scan . Two lung nodules disappeared
Oct 2018. Another clear scan .

Sam Phillips
Posts: 3
Joined: Wed Jun 10, 2020 8:32 am
Facebook Username: Sam Phillips

Re: CEA rising

Postby Sam Phillips » Sun Jun 21, 2020 9:00 am

Thankyou for your reply I thought it should go down while on chemo if chemo is working

Trying
Posts: 240
Joined: Sun May 13, 2018 10:11 pm

Re: CEA rising

Postby Trying » Sun Jun 21, 2020 4:38 pm

Hi there

I have learned that my CEA goes up and down. This seems to be a trend for my body.
38 yr old single mom of almost 2 year old at the time
April 2018 colon cancer stage IV 10 liver mets and peri met. Folfox and 12 rounds oxyplatin
Fec 2018 Down to 2 mets in liver. 8 dissapeared
July 2019 switched to xeloda pills as I prefer to 3 day infusion. Also on avistan
Oct 2019 emergency colostomy due to perforated bowel. ( unreal pain)
Feb 2020 show 2mm tumor increase.
Plan to go back on oxy

User avatar
beach sunrise
Posts: 121
Joined: Thu Mar 05, 2020 7:14 pm

Re: CEA rising

Postby beach sunrise » Mon Jun 22, 2020 2:45 pm

Hi Sam, mine was higher than when starting folfox and after 8 rounds still high. One thing a forum member brought to my attention was the MCV panel of your bloodwork. If it rises =>10 then good sign chemo is working. I found the NCI paper on MCV and chemo. Look it up.
Dx 8/19, RC, CEA 86, clinical T3N0M0
Neoadj 5FU/rad 6 wks
Surg 1-21-20 APR ostomy, neg margins T4bN1a IIIC G2 MSI- 1/20 LN+ LVI+ PNI-
presurg cea 24/post 5.9
Adj mFOLFOX6, cea 7
8 rds 6-10 CEA 11.4, 4 more no oxa
6-17: CEA 11.1 AFP 11.2 CA125 25.7 CA199 9
7-2: CEA 11.1 AFP 5.3 CA125 24.8 CA199 8
MHL1+
PMS2+
MSH2+
MSH6+
Chemo sensitivity test NCI "Test failed, neo-adj chemorad did its job. Not enough ca. cells to test."

stu
Posts: 1355
Joined: Sat Aug 17, 2013 5:46 pm

Re: CEA rising

Postby stu » Wed Jun 24, 2020 4:51 pm

Chemo itself can cause a rise after an initial decrease . My mum’s tumours were no longer visible on the scan but her CEA went higher than ever . It happened both years .
Take care ,
Stu
supporter to my mum who lives a great life despite a difficult diagnosis
stage4 2009 significant spread to liver
2010 colon /liver resection
chemo following recurrence
73% of liver removed
enjoying life treatment free
2016 lung resection
Oct 2017 nice clear scan . Two lung nodules disappeared
Oct 2018. Another clear scan .

Sam Phillips
Posts: 3
Joined: Wed Jun 10, 2020 8:32 am
Facebook Username: Sam Phillips

Re: CEA rising

Postby Sam Phillips » Sat Jun 27, 2020 7:37 am

Thankyou Everyone when I started chemo it was 0.8 now at 4.9 and has never fluctuated

stu
Posts: 1355
Joined: Sat Aug 17, 2013 5:46 pm

Re: CEA rising

Postby stu » Sat Jun 27, 2020 11:14 am

Hi ,
Tumour death can release CEA cells into the blood stream which can cause a rise during chemo or I think just chemo itself can do it . My mum’s tumour markers don’t rise much even with a spread but got up to 11 each year she was on chemo . I notice your markers are quite low too !
Given your good scan recently and slower growing nature so some lung mets I would hold onto that . The radiology evidence is usually more reliable .
Take care ,
Stu
supporter to my mum who lives a great life despite a difficult diagnosis
stage4 2009 significant spread to liver
2010 colon /liver resection
chemo following recurrence
73% of liver removed
enjoying life treatment free
2016 lung resection
Oct 2017 nice clear scan . Two lung nodules disappeared
Oct 2018. Another clear scan .


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