Claudine wrote:Hello Alex,
I had to google Zaltrap as I'd never heard of it. It looks like it's similar to Avastin, with the same goal of cutting blood access to the tumors. That part of the treatment shouldn't give your mom side effects that are different than when she was on Avastin - for my husband, it was bloody nose when he'd blow it, but that's about it. Your mom was on Avastin before; any reason they're switching to Zaltrap now?
Folfori - some people here report heavy fatigue, intense nausea; but not DH, compared with his previous chemo (Xeloda + Oxaliplatin) Folfiri was a breeze. A little fatigue, but not much; no nausea to speak of (except towards the end of treatment - he had 18 cycles) ; hair thinning, but he never got completely bald, and it's all grown back since.
But like I said, others have been hit really hard by Folfiri. Fingers crossed your mom isn't one of them, and that the treatment hits her mets hard!
boxhill wrote:Alex, why didn't your mom have chemo after surgery with lymph node involvement? How often was she scanned?
It sounds like things are back on track now, but I'm wondering if anyone has discussed maintenance chemo, assuming she responds to this? Has there been any discussion of any of the possible non-chemical lung treatments?
ETA: I just reread your post, and I'm not sure whether the liver lesions are gone...
Claudine wrote:Hello Alex,
I had to google Zaltrap as I'd never heard of it. It looks like it's similar to Avastin, with the same goal of cutting blood access to the tumors. That part of the treatment shouldn't give your mom side effects that are different than when she was on Avastin - for my husband, it was bloody nose when he'd blow it, but that's about it. Your mom was on Avastin before; any reason they're switching to Zaltrap now?
Folfori - some people here report heavy fatigue, intense nausea; but not DH, compared with his previous chemo (Xeloda + Oxaliplatin) Folfiri was a breeze. A little fatigue, but not much; no nausea to speak of (except towards the end of treatment - he had 18 cycles) ; hair thinning, but he never got completely bald, and it's all grown back since.
But like I said, others have been hit really hard by Folfiri. Fingers crossed your mom isn't one of them, and that the treatment hits her mets hard!
Alex83 wrote:Hello,
Today we went to lab to inspect the MSI.
does anyone has an idea about this test?
I read a lot of article about it, I came to know that there are 3 resuls: MSI-H (high) and MSI-L (low) and MSS (stable).
so which result is the best and how it helps the treatment?
Thank you
Alex83 wrote:Hello,
Today i got the result of (MSI)
no loss of nuclear expression of mmr proteins: Low probability of MSI-H, so that means the patient not a good candidate of immunotherapy?
Mom didn't take chemo after surgery since the doctor said everything are fine and no need to have chemo (it is just 3 nodes out of seven)
boxhill wrote:Mom didn't take chemo after surgery since the doctor said everything are fine and no need to have chemo (it is just 3 nodes out of seven)
Okay, I am not a doctor. But this has me fuming. In the first place, 7 is a VERY low number of lymph nodes to biopsy. Recommendations have varied, but AT LEAST 12 has been recommended, more if possible. The lower the number of nodes taken, the higher the chances of recurrence due to missed disease. As a patient with almost 50% of sampled lymph nodes positive, I think that most--if not all--competent oncologists would DEFINITELY recommend adjuvant chemo for a patient of your mother's age! And this wasn't a decade ago, this was 2017!!
Was this doctor a surgeon or an oncologist? Whatever his/her specialty, I sincerely hope your mother is not using that doctor now. It's not my business, I know, but I would have no confidence in him/her. I hate to see people get sub par treatment that doesn't even explore more aggressive strategies that aim for NED. It makes me angry.
Actually the surgeon did that during the surgery and he removed the tumor, whatever after 8 months we follow up with CT scan and it showed the metastases then we start with the oncologist.
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